dioxolanne de la chloro-4 bromo-4' benzophenone

Base Information

• Chemical Name: dioxolanne de la chloro-4 bromo-4' benzophenone
• CAS No.: 81223-63-4
• Molecular Formula: C₁₅H₁₂BrClO₂
• Molecular Weight: 339.616
• Mol file: 81223-63-4.mol

Synonyms:dioxolanne de la chloro-4 bromo-4' benzophenone

Chemical Property of dioxolanne de la chloro-4 bromo-4' benzophenone

Chemical Property:

Purity/Quality:

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Technology Process of dioxolanne de la chloro-4 bromo-4' benzophenone

There total 2 articles about dioxolanne de la chloro-4 bromo-4' benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

→ dioxolanne de la chloro-4 bromo-4' benzophenone (81223-63-4)

Guidance literature:

Reference yield: 82.0%

4-bromo-4'-chlorobenzophenone (27428-57-5) + ethylene glycol (107-21-1) → dioxolanne de la chloro-4 bromo-4' benzophenone (81223-63-4)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 48h; Heating;

Reference yield:

dioxolanne de la chloro-4 bromo-4' benzophenone (81223-63-4) → C19H20ClN2O(1+)*CH3O4S(1-)

Guidance literature:

Multi-step reaction with 7 steps

1: 1) n-butyllithium / 1) ether, -30 deg C, 2 h, 2) -40 deg C

2: 51 percent / Na / methanol / 12 h / -10 °C

3: 74 percent / xylene / 3 h / Heating

4: 68 percent / aq. KOH / 2 h / Heating

5: 70 percent / copper chromite (barium promoted) / quinoline / 3 h / 220 °C

6: 40 percent / methanol / 120 h / Heating

7: tetrahydrofuran; acetic acid / Ambient temperature

With n-butyllithium; sodium; CuO/Cr₂O₃; In tetrahydrofuran; quinoline; methanol; potassium hydroxide; acetic acid; xylene;

upstream raw materials:

4-bromo-4'-chlorobenzophenone

ethylene glycol

Downstream raw materials:

dioxolanne du p-chlorobenzoyl-4 benzaldehyde

4-(4-chlorobenzoyl)benzaldehyde

p-chlorobenzoyl-6 indole

acide p-chlorobenzoyl-6 indolecarboxylique-2

Refernces

• 1、 Kim, Phieo Ta,Guilard, Roger,Dodey, Pierre,Sornay, Roland. "Synthese d'acetyl-6 et benzoyl-6 indoles". . p. 1365 - 1371. Retrieved 2007/10/02.