7-Nitro-4-fluorenecarboxylic acid

Base Information

• Chemical Name: 7-Nitro-4-fluorenecarboxylic acid
• CAS No.: 7256-04-4
• Molecular Formula: C14H9 N O4
• Molecular Weight: 255.23
• Hs Code.: 2916399090
• European Community (EC) Number: 635-281-4
• NSC Number: 74985
• DSSTox Substance ID: DTXSID90291344
• Nikkaji Number: J1.938.413F
• Wikidata: Q82029278
• Mol file: 7256-04-4.mol

Synonyms:7-Nitro-4-fluorenecarboxylic acid;7256-04-4;7-nitro-9h-fluorene-4-carboxylic acid;NSC74985;NCIOpen2_004647;SCHEMBL1115137;7-Nitro-4-fluorencarboxylic acid;DTXSID90291344;NSC-74985;7-nitro-9h-fluorene-4-carboxylicacid;AKOS015894261;7-Nitro-4-fluorenecarboxylic acid, 95%

Chemical Property of 7-Nitro-4-fluorenecarboxylic acid

Chemical Property:

• Vapor Pressure: 4.64E-11mmHg at 25°C
• Melting Point: 250-265oC(lit.)
• Boiling Point: 506°C at 760 mmHg
• Flash Point: 218.2°C
• PSA: 83.12000
• Density: 1.477g/cm³
• LogP: 3.38740
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 255.05315777
• Heavy Atom Count: 19
• Complexity: 391

Purity/Quality:

98%,99%, ^*data from raw suppliers

7-NITRO-4-FLUORENECARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C2=C(C3=C1C=C(C=C3)[N+](=O)[O-])C(=CC=C2)C(=O)O

Technology Process of 7-Nitro-4-fluorenecarboxylic acid

There total 4 articles about 7-Nitro-4-fluorenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorene-4-carboxylic acid (6954-55-8) → 7-nitro-fluorene-4-carboxylic acid (7256-04-4) + 5-nitro-fluorene-4-carboxylic acid (7145-76-8)

Guidance literature:

With nitric acid; acetic acid;

DOI:10.1021/jo01127a018 DOI:10.1021/jo01112a610

Reference yield:

diphenic acid (863305-32-2) → 7-nitro-fluorene-4-carboxylic acid (7256-04-4)

Guidance literature:

Multi-step reaction with 3 steps

1: polyphosphoric acid

2: hydrazine

3: nitric acid; acetic acid / 65 - 70 °C

With PPA; nitric acid; acetic acid; hydrazine; 1: Cyclization / 2: Reduction / 3: Nitration;

DOI:10.1016/S0165-1218(96)90022-1

Reference yield:

9-oxo-9H-fluorene-4-carboxylic acid (6223-83-2) → 7-nitro-fluorene-4-carboxylic acid (7256-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine

2: nitric acid; acetic acid / 65 - 70 °C

With nitric acid; acetic acid; hydrazine; 1: Reduction / 2: Nitration;

DOI:10.1016/S0165-1218(96)90022-1

upstream raw materials:

fluorene-4-carboxylic acid

diphenic acid

9-oxo-9H-fluorene-4-carboxylic acid

Downstream raw materials:

5-Hydroxy-2-nitrofluorene

2,5-diaminofluorene

Refernces