N-Hydroxy-4-propoxy-benzamidine

Base Information

• Chemical Name: N-Hydroxy-4-propoxy-benzamidine
• CAS No.: 145259-49-0
• Molecular Formula: C10H14 N2 O2
• Molecular Weight: 194.233
• Hs Code.: 2925290090
• DSSTox Substance ID: DTXSID40383309
• Mol file: 145259-49-0.mol

Synonyms:N-Hydroxy-4-propoxy-benzamidine;145259-49-0;N'-hydroxy-4-propoxybenzenecarboximidamide;N'-hydroxy-4-propoxybenzene-1-carboximidamide;DTXSID40383309;OOCDAYWHISVQPO-UHFFFAOYSA-N;N/'-Hydroxy-4-propoxybenzenecarboximidamide

Chemical Property of N-Hydroxy-4-propoxy-benzamidine

Chemical Property:

• Melting Point: 105 °C
• Refractive Index: 1.539
• Boiling Point: 364°Cat760mmHg
• Flash Point: 174°C
• PSA: 67.84000
• Density: 1.14g/cm³
• LogP: 2.27020
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 194.105527694
• Heavy Atom Count: 14
• Complexity: 187

Purity/Quality:

98%min ^*data from raw suppliers

N''-hydroxy-4-propoxybenzenecarboximidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC1=CC=C(C=C1)C(=NO)N

Technology Process of N-Hydroxy-4-propoxy-benzamidine

There total 3 articles about N-Hydroxy-4-propoxy-benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-cyanophenyl propyl ether (60758-84-1) → N-hydroxy-4-propoxybenzamidine (145259-49-0)

Guidance literature:

With dmap; hydroxylamine hydrochloride; copper hydroxide; potassium hydroxide; In methanol; at 0 - 50 ℃; for 5h; under 60006 Torr; Inert atmosphere; Sealed tube; Supercritical conditions;

Reference yield:

→ N-hydroxy-4-propoxybenzamidine (145259-49-0)

Guidance literature:

Reference yield:

→ 4-propoxybenzamidoxime (145259-49-0)

Guidance literature:

upstream raw materials:

4-cyanophenyl propyl ether

Refernces

• 1、 -. "A role of the wicked two zuozuo kinds with anti-oxidation of the compound and its preparation method (by machine translation)". Paragraph 0023-0025. . Retrieved 2019/06/07.
• 2、 -. "AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS". Page/Page column 42. . Retrieved 2008/12/07.