n-Cbz-trans-1,4-cyclohexanediamine

Base Information Edit

Chemical Name:n-Cbz-trans-1,4-cyclohexanediamine
CAS No.:149423-77-8
Molecular Formula:C14H20N2O2
Molecular Weight:248.325
Hs Code.:2924299090
European Community (EC) Number:675-944-5
DSSTox Substance ID:DTXSID60933643
Mol file:149423-77-8.mol

Synonyms:149423-77-8;149423-70-1;Benzyl (trans-4-aminocyclohexyl)carbamate;n-cbz-trans-1,4-cyclohexanediamine;Benzyl (cis-4-aminocyclohexyl)carbamate;227017-99-4;Benzyl cis-4-aminocyclohexylcarbamate;benzyl (4-aminocyclohexyl)carbamate;(4-Amino-cyclohexyl)-carbamic acid benzyl ester;cis-N-Cbz-1,4-cyclohexanediamine;Cis-1-N-Cbz-1,4-Cyclohexyldiamine;1-n-cbz-trans-1,4-cyclohexyldiamine;benzyl N-(4-aminocyclohexyl)carbamate;C14H20N2O2;Benzyl ((1r,4r)-4-aminocyclohexyl)carbamate;benzyl trans-4-aminocyclohexylcarbamate;benzyl (1s,4s)-4-aminocyclohexylcarbamate;cis-4-(Benzyloxycarbonylamino)cyclohexylamine;Carbamic acid, (4-aminocyclohexyl)-, phenylmethyl ester (9CI);benzyl (1r,4r)-4-aminocyclohexylcarbamate;Carbamic acid, N-(trans-4-aminocyclohexyl)-, phenylmethyl ester;trans-N-Cbz-1,4-cyclohexanediamine;MFCD03839901;MFCD06657668;benzyl N-[(1r,4r)-4-aminocyclohexyl]carbamate;Carbamic acid, N-(cis-4-aminocyclohexyl)-, phenylmethyl ester;1-N-CBZ-CIS-1,4-CYCLOHEXYLDIAMINE;1-Cbz-amino-4-aminocyclohexane;Benzyl(trans-4-aminocyclohexyl)carbamate;(1R,4R)- (4-Amino-cyclohexyl)-carbamic acid benzyl ester;Carbamic acid, (4-aminocyclohexyl)-, phenylmethyl ester, cis-;Carbamic acid, (4-aminocyclohexyl)-, phenylmethyl ester, trans-;benzyl ((1s,4s)-4-aminocyclohexyl)carbamate;SCHEMBL760630;SCHEMBL880579;Cis-(4-Amino-cyclohexyl)-carbamic acid benzyl ester;SCHEMBL1192792;DTXSID60933643;JQVBZZUMWRXDSQ-BETUJISGSA-N;JQVBZZUMWRXDSQ-JOCQHMNTSA-N;JQVBZZUMWRXDSQ-UHFFFAOYSA-N;Benzyl(4-aminocyclohexyl)carbamate;CJA01799;ZFA42377;4-Amino-1-(Cbz-amino)-cyclohexane;AKOS015836900;AKOS015913670;AKOS017344480;AC-9237;CS-W003299;CS-W022586;GS-6469;SB11914;AM100269;AM100540;Benzyl trans-(4-aminocyclohexyl)carbamate;CS-11595;DS-18167;SY025971;SY112786;cis-N-Cbz-1 pound not4-cyclohexanediamine;benzyl N-[trans-4-aminocyclohexyl]carbamate;DB-012575;DB-208343;CS-0449918;(4-Aminocyclohexyl)carbamic acid benzyl ester;F52830;trans-4-(Benzyloxycarbonylamino)cyclohexylamine;Benzyl hydrogen (4-aminocyclohexyl)carbonimidate;A808888;(cis-4-amino-cyclohexyl)-carbamic acid benzyl ester;J-520063;Q-102412;BENZYL N-[(1S,4S)-4-AMINOCYCLOHEXYL]CARBAMATE;(1R,4R)-(4-Amino-cyclohexyl)-carbamic acid benzyl ester;(trans)-(4-Aminocyclohexyl)carbamic acid phenylmethyl ester;Carbamic acid,(cis-4-aminocyclohexyl)-,phenylmethyl ester(9ci)

Suppliers and Price of n-Cbz-trans-1,4-cyclohexanediamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
trans-4-(Benzyloxycarbonylamino)cyclohexylamine
1g
$ 75.00

Matrix Scientific
Benzyl trans-4-aminocyclohexylcarbamate
25g
$ 1143.00

Matrix Scientific
Benzyl trans-4-aminocyclohexylcarbamate
5g
$ 308.00

Matrix Scientific
Benzyl trans-4-aminocyclohexylcarbamate
1g
$ 103.00

Crysdot
Benzyl(trans-4-aminocyclohexyl)carbamate 95+%
5g
$ 277.00

Crysdot
Benzyl(trans-4-aminocyclohexyl)carbamate 95+%
1g
$ 99.00

Crysdot
Benzyl(trans-4-aminocyclohexyl)carbamate 95+%
10g
$ 446.00

Crysdot
Benzyl(trans-4-aminocyclohexyl)carbamate 95+%
25g
$ 892.00

Chemenu
Benzyl(trans-4-aminocyclohexyl)carbamate 95%
25g
$ 842.00

Chemenu
Benzyl(trans-4-aminocyclohexyl)carbamate 95%
10g
$ 421.00

Total 41 raw suppliers

Chemical Property of n-Cbz-trans-1,4-cyclohexanediamine Edit

Chemical Property:

Vapor Pressure:6.47E-07mmHg at 25°C
Refractive Index:1.561
Boiling Point:409.5 °C at 760 mmHg
PKA:12.23±0.40(Predicted)
Flash Point:201.5 °C
PSA：64.35000
Density:1.13 g/cm³
LogP:3.27390
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Water Solubility.:Slightly soluble in water.
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:257

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-4-(Benzyloxycarbonylamino)cyclohexylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CCC1N)NC(=O)OCC2=CC=CC=C2
Uses trans-4-(Benzyloxycarbonylamino)cyclohexylamine is used as pharmaceutical intermediate.

Technology Process of n-Cbz-trans-1,4-cyclohexanediamine

There total 3 articles about n-Cbz-trans-1,4-cyclohexanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%