2-METHOXY-9H-CARBAZOLE

Base Information

• Chemical Name: 2-METHOXY-9H-CARBAZOLE
• CAS No.: 6933-49-9
• Molecular Formula: C13H11NO
• Molecular Weight: 197.236
• Hs Code.: 2933990090
• European Community (EC) Number: 811-118-4
• DSSTox Substance ID: DTXSID90445007
• Nikkaji Number: J2.027.195G
• Wikidata: Q82263318
• ChEMBL ID: CHEMBL1170443
• Mol file: 6933-49-9.mol

Synonyms:2-METHOXY-9H-CARBAZOLE

Chemical Property of 2-METHOXY-9H-CARBAZOLE

Chemical Property:

• Melting Point: 239℃
• Boiling Point: 392.2±15.0 °C(Predicted)
• PKA: 16.74±0.30(Predicted)
• PSA: 25.02000
• Density: 1.232±0.06 g/cm3(Predicted)
• LogP: 3.32970
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 197.084063974
• Heavy Atom Count: 15
• Complexity: 231

Purity/Quality:

98% ^*data from raw suppliers

2-Methoxy-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)C3=CC=CC=C3N2

Technology Process of 2-METHOXY-9H-CARBAZOLE

There total 70 articles about 2-METHOXY-9H-CARBAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-azido-4'-methoxy-1,1'-biphenyl (29511-98-6) → 2-methoxy-9H-carbazole (6933-49-9)

Guidance literature:

With sulfur-modified Au-supported iron⁽⁰⁾ nanoparticles; In 1,4-dioxane; at 110 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c02574

Reference yield: 95.0%

1-azido-2-iodo-benzene (54467-95-7) + 3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) → 2-methoxy-9H-carbazole (6933-49-9)

Guidance literature:

1-azido-2-iodo-benzene; 3-methoxyphenylboronic acid; With potassium carbonate; In 1,4-dioxane; at 110 ℃; for 8h; Inert atmosphere;

In 1,4-dioxane; water; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.0c02574

Reference yield: 93.0%

4'-methoxy-2-nitrobiphenyl (20013-55-2) → 2-methoxy-9H-carbazole (6933-49-9)

Guidance literature:

With triethyl phosphite; for 16h; Heating / reflux;

upstream raw materials:

2-hydroxycarbazole

dimethyl sulfate

7-methoxy-2,3,4,9-tetrahydro-1H-carbazole

2-azido-4'-methoxy-1,1'-biphenyl

Downstream raw materials:

2-methoxy-9-phenyl-9H-carbazole

Refernces

• 1、 -. "Preparation method of carbazole and fluorene organic electroluminescent intermediates". Paragraph 0041-0044. . Retrieved 2021/07/14.
• 2、 Qu, Zhonghua,Chen, Xing,Zhong, Shuai,Deng, Guo-Jun,Huang, Huawen. "NaI/PPh3-Mediated Photochemical Reduction and Amination of Nitroarenes". supporting information. p. 5349 - 5353. Retrieved 2021/07/21.