4'-METHOXY-2-NITROBIPHENYL

Base Information

• Chemical Name: 4'-METHOXY-2-NITROBIPHENYL
• CAS No.: 20013-55-2
• Molecular Formula: C13H11NO3
• Molecular Weight: 229.235
• Hs Code.: 2909309090
• Mol file: 20013-55-2.mol

Synonyms:1,1'-Biphenyl,4'-methoxy-2-nitro;2-nitro-4'-methoxybiphenyl;4-methoxy-2'-nitro-biphenyl;4-methoxy-2'-nitro-1,1'-biphenyl;

Chemical Property of 4'-METHOXY-2-NITROBIPHENYL

Chemical Property:

• Melting Point: 58-62 °C
• Boiling Point: 142 °C(Press: 2 Torr)
• PSA: 55.05000
• Density: 1.202±0.06 g/cm3(Predicted)
• LogP: 3.79360

Purity/Quality:

98%min ^*data from raw suppliers

4'-METHOXY-2-NITROBIPHENYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4'-METHOXY-2-NITROBIPHENYL

There total 47 articles about 4'-METHOXY-2-NITROBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

o-nitroiodobenzene (609-73-4) + 4-methoxyphenylboronic acid (5720-07-0) → 4'-methoxy-2-nitrobiphenyl (20013-55-2)

Guidance literature:

With potassium carbonate; In ethanol; at 80 ℃; for 0.5h; Reagent/catalyst; Catalytic behavior;

DOI:10.1055/s-0040-1705989

Reference yield: 98.0%

4-methoxyphenylboronic acid (5720-07-0) + 2-Chloronitrobenzene (88-73-3) → 4'-methoxy-2-nitrobiphenyl (20013-55-2)

Guidance literature:

With potassium phosphate tribasic trihydrate; (2-mesityl-1H-inden-3-yl)dicyclohexyl phosphine; palladium diacetate; Aliquat 336; In water; at 20 - 100 ℃; for 8h; Inert atmosphere;

DOI:10.1039/c2ob26463c

Reference yield: 97.0%

1-(2'-nitrophenyl)-3,3-dimethyltriazene (20241-01-4) + di-(4-methoxyphenyl)borinic acid (73774-45-5) → 4'-methoxy-2-nitrobiphenyl (20013-55-2)

Guidance literature:

With BF₃O(CH₂CH₂)2O; palladium diacetate; In 1,4-dioxane; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2019.151491

upstream raw materials:

4-methoxy-N-nitrosoacetanilide

2-Nitrophenyldiazonium

methoxybenzene

4'-hydroxy-2-nitrobiphenyl

Downstream raw materials:

8-methoxyphenanthridine-6(5H)-one

4-chloro-benzoic acid-(4'-methoxy-biphenyl-2-ylamide)

6-(4-chloro-phenyl)-8-methoxy-phenanthridine

2-methoxy-9H-carbazole

Refernces

• 1、 Simamura,Migita. "-". . p. 228,230. Retrieved 1954.
• 2、 Goetz, Roland,Hashmi, A. Stephen K.,Orecchia, Patrizio,Petkova, Desislava Slavcheva,Rominger, Frank,Schaub, Thomas. "Pd-Catalysed Suzuki-Miyaura cross-coupling of aryl chlorides at low catalyst loadings in water for the synthesis of industrially important fungicides". supporting information. p. 8169 - 8180. Retrieved 2021/11/01.
• 3、 Qu, Zhonghua,Wang, Pu,Chen, Xing,Deng, Guo-Jun,Huang, Huawen. "Visible-light-driven Cadogan reaction". supporting information. p. 2582 - 2586. Retrieved 2021/03/09.