Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI)

Base Information

• Chemical Name: Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI)
• CAS No.: 6090-37-5
• Molecular Formula: C5H5FN2S
• Molecular Weight: 144.1700032
• Hs Code.: 2933599590
• Mol file: 6090-37-5.mol

Synonyms:Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI)

Chemical Property of Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI)

Chemical Property:

• PSA: 51.08000
• LogP: 1.33760

Purity/Quality:

95% ^*data from raw suppliers

5-Fluoro-2-(methylthio)pyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI)

There total 1 articles about Pyrimidine, 5-fluoro-2-(methylthio)- (7CI,8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Cl(1-)*C27H36ClN2(1+)*Cs(1+)*F(1-) + 2-methylthio-5-hydroxypyrimidine (4874-33-3) → 5-fluoro-2-(methylthio)pyrimidine (6090-37-5)

Guidance literature:

In toluene; at 23 - 110 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol5035518

upstream raw materials:

2-methylthio-5-hydroxypyrimidine

Refernces