3-CHLORO-ALANINEMETHYL ESTER

Base Information

• Chemical Name: 3-CHLORO-ALANINEMETHYL ESTER
• CAS No.: 56410-68-5
• Molecular Formula: C4H8ClNO2
• Molecular Weight: 137.566
• Mol file: 56410-68-5.mol

Synonyms:3-CHLORO-ALANINEMETHYL ESTER

Chemical Property of 3-CHLORO-ALANINEMETHYL ESTER

Chemical Property:

• PSA: 52.32000
• LogP: 0.42580

Purity/Quality:

97% ^*data from raw suppliers

METHYL 2-AMINO-3-CHLOROPROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-CHLORO-ALANINEMETHYL ESTER

There total 4 articles about 3-CHLORO-ALANINEMETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Ser-OMe (2104-89-4,2788-84-3,24184-43-8) → 3-chloro-DL-alanine methyl ester (56410-68-5)

Guidance literature:

With phosphorus pentachloride; acetyl chloride; for 2.5h; 0 deg C -> rt;

DOI:10.1016/0040-4039(91)80558-N

Reference yield:

→ 3-chloro-DL-alanine methyl ester (56410-68-5)

Guidance literature:

DOI:10.1021/ja01183a111

Reference yield:

serin (302-84-1,83245-15-2) + phosphorus pentachloride (10026-13-8,874483-75-7) + acetyl chloride (75-36-5) → 3-chloro-DL-alanine methyl ester (56410-68-5)

Guidance literature:

l-serine; der Methylester des l-Serins reagiert;

upstream raw materials:

Ser-OMe

serin

phosphorus pentachloride

acetyl chloride

Downstream raw materials:

meso-lanthionine

DL,DL-cystathionine

D,L-selenocystine

methyl 2-benzamido-3-chloro-propanoate

Refernces

• 1、 Esslinger, C. Sean,Koch, Hans P.,Kavanaugh, Michael P.,Philips, Dean P.,Chamberlin, A. Richard,Thompson, Charles M.,Bridges, Richard J.. "Structural determinants of substrates and inhibitors: Probing glutamate transporters with 2,4-methanopyrrolidine-2,4-dicarboxylate". . p. 3101 - 3106. Retrieved 2007/10/03.