m-Fluorophenyl trifluoromethanesulfonate

Base Information

• Chemical Name: m-Fluorophenyl trifluoromethanesulfonate
• CAS No.: 57606-65-2
• Molecular Formula: C7H4F4O3S
• Molecular Weight: 244.167
• Hs Code.: 2905190098
• Mol file: 57606-65-2.mol

Synonyms:m-Fluorophenyl trifluoromethanesulfonate;3-Fluorophenyl trifluoromethanesulphonate

Chemical Property of m-Fluorophenyl trifluoromethanesulfonate

Chemical Property:

• Boiling Point: 235.6±40.0 °C(Predicted)
• PSA: 51.75000
• Density: 1.574±0.06 g/cm3(Predicted)
• LogP: 3.13490

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of m-Fluorophenyl trifluoromethanesulfonate

There total 5 articles about m-Fluorophenyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

trifluoromethylsulfonic anhydride (358-23-6) + 3-fluorophenol (372-20-3) → m-fluorophenyl trifluoromethanesulfonate (57606-65-2)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 6h; Inert atmosphere;

DOI:10.1055/s-0037-1611053

Reference yield: 72.0%

m-fluorophenyldiazonium trifluoromethanesulfonate → m-fluorophenyl trifluoromethanesulfonate (57606-65-2)

Guidance literature:

at 110 - 120 ℃; for 1h;

DOI:10.1134/S1070428006080148

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + 3-fluorophenol (372-20-3) → m-fluorophenyl trifluoromethanesulfonate (57606-65-2) + sodium carbonate (497-19-8)

Guidance literature:

With NaOH; In tetrachloromethane;

upstream raw materials:

trifluoromethylsulfonic anhydride

3-fluorophenol

Downstream raw materials:

3-(3-fluorophenyl)quinoline

N-(3-fluorophenyl)thiazol-2-amine

2-(3-fluorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-fluoro-3-pentylbenzene

Refernces

• 1、 Quesnelle, Claude A.,Snieckus, Victor. "Directed ortho Metalation (D o M)-Linked Corriu-Kumada, Negishi, and Suzuki-Miyaura Cross-Coupling Protocols: A Comparative Study". supporting information. p. 4395 - 4412. Retrieved 2018/11/21.
• 2、 Rosas Vargas, Daisy,Cook, Silas P.. "Palladium nanoparticles: Chemoselective control for reductive Heck with aryl triflates and 2,3-dihydrofuran". supporting information. p. 3314 - 3317. Retrieved 2018/05/04.