Carbonocyanidic acid, phenyl ester

Base Information

• Chemical Name: Carbonocyanidic acid, phenyl ester
• CAS No.: 5532-82-1
• Molecular Formula: C8H5NO2
• Molecular Weight: 147.133
• Hs Code.: 2926909090
• Mol file: 5532-82-1.mol

Synonyms:Carbonocyanidic acid, phenyl ester

Chemical Property of Carbonocyanidic acid, phenyl ester

Chemical Property:

• PSA: 50.09000
• LogP: 1.11558

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbonocyanidic acid, phenyl ester

There total 7 articles about Carbonocyanidic acid, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,4-diaza-bicyclo[2.2.2]octane (280-57-9,88935-43-7) + trimethylsilyl cyanide (7677-24-9) + phenyl chloroformate (1885-14-9) → Phenyl cyanoformate (5532-82-1)

Guidance literature:

Reference yield: 75.0%

copper(I) cyanide (544-92-3) + Phenyl carbonoiodidate (88842-51-7) → Phenyl cyanoformate (5532-82-1)

Guidance literature:

In dichloromethane; acetonitrile; for 2h; Ambient temperature;

DOI:10.1021/jo00181a005

Reference yield:

phenyl chloroformate (1885-14-9) → Phenyl cyanoformate (5532-82-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / NaI / acetonitrile / 1 h / 70 °C

2: 75 percent / acetonitrile; CH₂Cl₂ / 2 h / Ambient temperature

With sodium iodide; In dichloromethane; acetonitrile;

DOI:10.1021/jo00181a005

upstream raw materials:

tetraethylammoniumcyanide

phenyl chloroformate

potassium cyanide

carbonyl cyanide

Downstream raw materials:

bis(phenyl) carbonate

Refernces

• 1、 Hoffmann, H.M.R.,Iranshahi, Lotfollah. "Synthesis an CuCN-Promoted Cyanation of Iodoformic Esters". . p. 1174 - 1176. Retrieved 2007/10/02.