4-Chlorophenyl 2-chloro-4-nitrophenyl ketone

Base Information

• Chemical Name: 4-Chlorophenyl 2-chloro-4-nitrophenyl ketone
• CAS No.: 50274-64-1
• Molecular Formula: C13H7 Cl2 N O3
• Molecular Weight: 296.109
• Hs Code.: 2914700090
• European Community (EC) Number: 256-514-2
• DSSTox Substance ID: DTXSID20198276
• Nikkaji Number: J308.235K
• Wikidata: Q83071049
• Mol file: 50274-64-1.mol

Synonyms:4-Chlorophenyl 2-chloro-4-nitrophenyl ketone;50274-64-1;(2-chloro-4-nitrophenyl)-(4-chlorophenyl)methanone;2,4'-dichloro-4-nitrobenzophenone;EINECS 256-514-2;(2-chloro-4-nitrophenyl)(4-chlorophenyl)methanone;C13H7Cl2NO3;SCHEMBL1149258;C13-H7-Cl2-N-O3;DTXSID20198276;AKOS024333052;(2-chloro-4-nitrophenyl)-(4'-chlorophenyl)methanone

Chemical Property of 4-Chlorophenyl 2-chloro-4-nitrophenyl ketone

Chemical Property:

• Vapor Pressure: 3.76E-08mmHg at 25°C
• Melting Point: 117-118.5 °C
• Boiling Point: 446°C at 760 mmHg
• Flash Point: 223.6°C
• PSA: 62.89000
• Density: 1.456g/cm³
• LogP: 4.65580
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 294.9802985
• Heavy Atom Count: 19
• Complexity: 350

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4'-DICHLORO-4-NITROBENZOPHENONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=O)C2=C(C=C(C=C2)[N+](=O)[O-])Cl)Cl

Technology Process of 4-Chlorophenyl 2-chloro-4-nitrophenyl ketone

There total 4 articles about 4-Chlorophenyl 2-chloro-4-nitrophenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.5%

2-chloro-4-nitrobenzoyl chloride (7073-36-1) + chlorobenzene (108-90-7) → (2-chloro-4-nitrophenyl)(4-chlorophenyl)-methanone (50274-64-1)

Guidance literature:

With aluminium trichloride; In chloroform; a) RT, overnight, b) reflux, 1 h;

DOI:10.1021/jm00355a019

Reference yield: 81.0%

hexane (110-54-3) + 2-chloro-4-nitrobenzoyl chloride (7073-36-1) + chlorobenzene (108-90-7) → (2-chloro-4-nitrophenyl)(4-chlorophenyl)-methanone (50274-64-1)

Guidance literature:

aluminium trichloride; In water; ethyl acetate; toluene;

Reference yield: 50.0%

2-chloro-4-nitrobenzoic acid (99-60-5) → (2-chloro-4-nitrophenyl)(4-chlorophenyl)-methanone (50274-64-1)

Guidance literature:

In chlorobenzene;

upstream raw materials:

2-chloro-4-nitrobenzoyl chloride

chlorobenzene

2-chloro-4-nitrobenzoic acid

hexane

Downstream raw materials:

(4-amino-2-chlorophenyl)(4-chlorophenyl)-methanone

{2-[3-chloro-4-(4-chloro-benzoyl)-phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonyl}-carbamic acid ethyl ester

2-<3-chloro-4-(4-chlorobenzoyl)phenyl>-1,2,4-triazine-3,5(2H,4H)-dione

(2-{[3-Chloro-4-(4-chloro-benzoyl)-phenyl]-hydrazono}-3-ethoxycarbonylamino-3-oxo-propionyl)-carbamic acid ethyl ester

Refernces

• 1、 -. "QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT". Page/Page column 106. . Retrieved 2010/10/19.
• 2、 -. "Benzophenones and benzhydrols". . . Retrieved 2008/06/13.