6-(Methylamino)hexan-1-ol

Base Information

• Chemical Name: 6-(Methylamino)hexan-1-ol
• CAS No.: 50347-17-6
• Molecular Formula: C7H17NO
• Molecular Weight: 131.218
• Hs Code.: 2922199090
• DSSTox Substance ID: DTXSID10449087
• Nikkaji Number: J838.764H
• Mol file: 50347-17-6.mol

Synonyms:6-(Methylamino)hexan-1-ol;50347-17-6;6-methylaminohexan-1-ol;6-(Methylamino)-1-hexanol;SCHEMBL1309714;DTXSID10449087;RURWAYHDLRPVAE-UHFFFAOYSA-N;MFCD00046026;AKOS006274839;AT11159;SB84533;SS-4245;FT-0621229;J-518082

Chemical Property of 6-(Methylamino)hexan-1-ol

Chemical Property:

• Vapor Pressure: 0.081mmHg at 25°C
• Refractive Index: 1.44
• Boiling Point: 200.282°C at 760 mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 62.403°C
• PSA: 32.26000
• Density: 0.872g/cm³
• LogP: 1.14940
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 131.131014166
• Heavy Atom Count: 9
• Complexity: 48.2

Purity/Quality:

98%Min ^*data from raw suppliers

6-(Methylamino)hexan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNCCCCCCO

Technology Process of 6-(Methylamino)hexan-1-ol

There total 9 articles about 6-(Methylamino)hexan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ N-Methyl-6-hydroxyhexylamine (50347-17-6)

Guidance literature:

In ethanol; at 60 ℃; for 16h;

Reference yield: 75.0%

6-(N-ethoxycarbonylamino)hexanoic acid (4143-15-1) → N-Methyl-6-hydroxyhexylamine (50347-17-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 12h; Heating;

DOI:10.1055/s-2003-42483

Reference yield: 63.0%

N-methyl-N-(triphenylsilyl)-6-(triphenylsyloxy)-1-hexanamine → N-Methyl-6-hydroxyhexylamine (50347-17-6)

Guidance literature:

With naphthalene; lithium; In tetrahydrofuran; methanol; at 20 ℃; for 6h;

DOI:10.1016/j.tet.2005.03.145

upstream raw materials:

6-chloro-1-hexanol

methylamine

6-(N-ethoxycarbonylamino)hexanoic acid

6-aminohexanoic acid

Downstream raw materials:

6-(N,N-dimethylamino)-1-hexanol

N-methylhex-5-en-1-amine

Refernces

• 1、 -. "Ligand, metal complex containing ligand, and reaction using metal complex containing ligand". Page/Page column 46-50. . Retrieved 2016/10/31.
• 2、 Miura, Takashi,Held, Ingmar E.,Oishi, Shunsuke,Naruto, Masayuki,Saito, Susumu. "Catalytic hydrogenation of unactivated amides enabled by hydrogenation of catalyst precursor". supporting information. p. 2674 - 2678. Retrieved 2013/06/26.