DL-NORPHENYLEPHRINE HYDROCHLORIDE

Base Information

• Chemical Name: DL-NORPHENYLEPHRINE HYDROCHLORIDE
• CAS No.: 636-87-3
• Molecular Formula: C8H12ClNO2
• Molecular Weight: 189.642
• Mol file: 636-87-3.mol

Synonyms:A-AMINOMETHYL-M-HYDROXYBENZYLALCOHOL HYDROCHLORIDE;(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE;NORPHENYLEPHRINE HYDROCHLORIDE;M-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE;TIMTEC-BB SBB000279;NORPHENYLEPHRINE HYDROCHLORIDE 98%;NorphenylephrineHCl;Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride, (R)- (9CI)

Chemical Property of DL-NORPHENYLEPHRINE HYDROCHLORIDE

Chemical Property:

• Melting Point: 162-164 °C(lit.)
• PSA: 66.48000
• LogP: 1.88660

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (R)-Norphenylephrine Hydrochloric Salt is an adrenergic agent used as a sympathomimetic drug.

Technology Process of DL-NORPHENYLEPHRINE HYDROCHLORIDE

There total 3 articles about DL-NORPHENYLEPHRINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.1%

phenylephrine hydrochloride (61-76-7,827-62-3) → (-)-m-octopamine (636-87-3)

Guidance literature:

for 9h; Irradiation;

Reference yield:

(+/-)-norphenylephrine hydrochloride (4779-94-6) → (-)m-octopamine hydrochloride (636-87-3,4779-94-6,15308-34-6,43090-68-2)

Guidance literature:

Reference yield:

(+/-)-norphenylephrine hydrochloride (4779-94-6) → (+)m-octopamine hydrochloride (43090-68-2) + (-)-m-octopamine (636-87-3)

Guidance literature:

With chiral stationary phase including isopropyl-functionalized CF₆; In methanol; acetic acid; triethylamine; acetonitrile; at 20 ℃; Purification / work up;

upstream raw materials:

(+/-)-norphenylephrine hydrochloride

phenylephrine hydrochloride

Downstream raw materials:

benzyl 4-(4-(4-((R)-2-hydroxy-2-(3-hydroxyphenyl)ethylamino)pentyl)phenyl)butylcarbamate

Refernces

• 1、 -. "COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS". Page/Page column 45-49; 58. . Retrieved 2010/12/31.