2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine

Base Information

• Chemical Name: 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine
• CAS No.: 869718-87-6
• Molecular Formula: C₅H₁₃NO₂
• Molecular Weight: 119.164
• Mol file: 869718-87-6.mol

Synonyms:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-Tetracosaoxatriheptacontan-73-amine;2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine;Aminopoly(ethylene glycol) methyl ether; Genamin MP 41-2000; MPEG-NH2;O-(2-Aminoethyl)-O'-methylpolyethylene glycol; Poly(ethylene glycol)2-aminoethyl methyl ether; Polyethylene glycol mono(2-aminoethyl) monomethylether; a-Amino-w-methoxy polyoxyethylene; a-Amino-w-methoxypolyethyleneglycol; a-Aminoethyl-w-methoxy polyethylene glycol; a-Methoxy-w-aminopoly(ethyleneglycol); a-Methyl-w-aminopoly(oxy-1,2-ethanediyl)

Chemical Property of 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

mPEG12-NH2 >=95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Technology Process of 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine

There total 58 articles about 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(2-(2-methoxyethoxy)ethoxy)ethyl azide (74654-06-1,89485-61-0) → 2-[2-(2-methoxyethoxy)ethoxy]ethylamine (74654-07-2,80506-64-5,869718-87-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 1h; Inert atmosphere;

Reference yield: 98.0%

1-azido-2-[2-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethane (1043884-49-6,89485-61-0) → 3,6,9,12-tetraoxa-tridecylamine (85030-56-4,80506-64-5,869718-87-6)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.3390/molecules200916085

Reference yield: 97.0%

1-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}-2-methoxyethane (606130-90-9,89485-61-0) → 3,6,9,12-tetraoxa-tridecylamine (85030-56-4,80506-64-5,869718-87-6)

Guidance literature:

1-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}-2-methoxyethane; With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 24h;

With water; In tetrahydrofuran; for 24h;

DOI:10.1021/ja035558w

upstream raw materials:

16-azido-2,5,8,11,14-pentaoxahexadecane

3,6,9,12,15-pentaoxahexadecanol

3,6,9,12,15-pentaoxahexadecyl tosylate

2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate

Downstream raw materials:

mPEG₃-N-diphenhydramine

Refernces

• 1、 -. "Novel method for preparing tris (3,6 -dioxo-heptyl) amine". Paragraph 0037; 0050-0054; 0059-0062; 0067-0070. . Retrieved 2021/04/14.
• 2、 Pineux, Florent,Federico, Stephanie,Klotz, Karl-Norbert,Kachler, Sonja,Michiels, Carine,Sturlese, Mattia,Prato, Maurizio,Spalluto, Giampiero,Moro, Stefano,Bonifazi, Davide. "Targeting G Protein-Coupled Receptors with Magnetic Carbon Nanotubes: The Case of the A3 Adenosine Receptor". supporting information. p. 1909 - 1920. Retrieved 2020/09/11.