4-TRIFLUOROMETHYLPHTHALIC ACID

Base Information

• Chemical Name: 4-TRIFLUOROMETHYLPHTHALIC ACID
• CAS No.: 835-58-5
• Molecular Formula: C9H5F3O4
• Molecular Weight: 234.132
• Hs Code.: 29173990
• Mol file: 835-58-5.mol

Synonyms:Phthalicacid, 4-(trifluoromethyl)- (6CI,7CI,8CI);4-(Trifluoromethyl)phthalic acid;

Chemical Property of 4-TRIFLUOROMETHYLPHTHALIC ACID

Chemical Property:

• Melting Point: 151 °C
• Boiling Point: 350.9 °C at 760 mmHg
• PKA: 2.74±0.10(Predicted)
• Flash Point: 166 °C
• PSA: 74.60000
• Density: 1.581 g/cm³
• LogP: 2.10180
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Trifluoromethyl)phthalicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-TRIFLUOROMETHYLPHTHALIC ACID

There total 6 articles about 4-TRIFLUOROMETHYLPHTHALIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,2-dimethyl-4-(trifluoromethyl)benzene (78164-31-5) → 4-(trifluoromethyl)phthalic acid (835-58-5)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; In acetic acid; at 15 - 40 ℃; for 4h;

Reference yield:

methyl 2-cyano-4-trifluoromethyl-benzoate (61500-86-5) + pyrographite (7440-44-0) → 4-(trifluoromethyl)phthalic acid (835-58-5)

Guidance literature:

With hydrogenchloride; In methanol; water;

Reference yield:

2-(trifluoromethyl)naphthalene (581-90-8) → 4-(trifluoromethyl)phthalic acid (835-58-5)

Guidance literature:

With pyridine; potassium permanganate;

upstream raw materials:

maleic anhydride

2-trifluoromethyl-1,3-butadiene

1,2-dimethyl-4-(trifluoromethyl)benzene

2-(trifluoromethyl)naphthalene

Downstream raw materials:

5-trifluoromethylbenzofuran-1,3-dione

2-(4-Chlor-phenyl)-5-trifluormethyl-1,3-indandion

2-phenyl-5-trifluoromethylindan-1,3-dione

2-(3'-Methylphenyl)-5-trifluormethyl-1,3-indandion

Refernces

• 1、 Pawlowski, Georg,Hanack, Michael. "A CONVENIENT SYNTHESIS OF TRIFLUOROMETHYL SUBSTITUTED PHTHALOCYANINES". . p. 351 - 364. Retrieved 2007/10/02.
• 2、 -. "Naphthyridine derivatives". . . Retrieved 2008/06/13.