Phenyl cyclohexanecarboxylate

Base Information

• Chemical Name: Phenyl cyclohexanecarboxylate
• CAS No.: 3954-12-9
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Hs Code.: 2916209090
• Mol file: 3954-12-9.mol

Synonyms:cyclohexanecarboxylic acid, phenyl ester;

Chemical Property of Phenyl cyclohexanecarboxylate

Chemical Property:

• Boiling Point: 300.6 °C at 760 mmHg
• Flash Point: 108.1 °C
• PSA: 26.30000
• Density: 1.077 g/cm³
• LogP: 3.17230

Purity/Quality:

98%Min ^*data from raw suppliers

PHENYL CYCLOHEXANECARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenyl cyclohexanecarboxylate

There total 17 articles about Phenyl cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + cyclohexanol (108-93-0) → phenyl cyclohexanecarboxylate (3954-12-9)

Guidance literature:

With Fe^III-salen; cyclohexylamine; for 10h; Reflux;

Reference yield: 98.0%

phenol (108-95-2,27073-41-2) + Cyclohexanecarboxylic acid (98-89-5) → phenyl cyclohexanecarboxylate (3954-12-9)

Guidance literature:

With magnesium hydroxide; lithium hydroxide monohydrate; di-tert-butyl dicarbonate; at 25 ℃; for 24h; Reagent/catalyst;

Reference yield: 92.0%

cyclohexanylcarbonyl chloride (2719-27-9) + phenol (108-95-2,27073-41-2) → phenyl cyclohexanecarboxylate (3954-12-9)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1039/d1ob00187f

upstream raw materials:

Perbenzoic acid

chloroform

Cyclohexyl phenyl ketone

sodium phenoxide

Downstream raw materials:

1,1-biscyclohexanemethanol

S-(4-methoxyphenyl) cyclohexanecarbothioate

4-cyclohexylcarbonyl-1-hydroxybenzene

cyclohexyl(2-hydroxyphenyl)methanone

Refernces

• 1、 Huang, Changyu,Li, Jinpeng,Wang, Jiaquan,Zheng, Qingshu,Li, Zhenhua,Tu, Tao. "Hydrogen-bond-assisted transition-metal-free catalytic transformation of amides to esters". . p. 66 - 71. Retrieved 2020/11/18.
• 2、 -. "Method for preparing carboxylate aryl type compound". Paragraph 0107-0112. . Retrieved 2020/02/10.