Magnesium;1,4-dimethylbenzene-6-ide;bromide

Base Information

• Chemical Name: Magnesium;1,4-dimethylbenzene-6-ide;bromide
• CAS No.: 30897-86-0
• Molecular Formula: C8H9BrMg
• Molecular Weight: 209.368
• Hs Code.: 29319090
• DSSTox Substance ID: DTXSID20450462
• Mol file: 30897-86-0.mol

Synonyms:magnesium;1,4-dimethylbenzene-6-ide;bromide;DTXSID20450462

Chemical Property of Magnesium;1,4-dimethylbenzene-6-ide;bromide

Chemical Property:

• Boiling Point: 65 °C(lit.)
• Flash Point: 1 °F
• PSA: 0.00000
• Density: 0.945 g/mL at 25 °C(lit.)
• LogP: 2.94920
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 207.97380
• Heavy Atom Count: 10
• Complexity: 169

Purity/Quality:

98% ^*data from raw suppliers

2,5-Dimethylphenylmagnesium bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C,F+
• Hazard Codes: F,C,F+,Xn
• Statements: 11-14-19-22-34-40-12-36/37
• Safety Statements: 16-23-26-36/37/39-45-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C[C-]=C(C=C1)C.[Mg+2].[Br-]

Technology Process of Magnesium;1,4-dimethylbenzene-6-ide;bromide

There total 1 articles about Magnesium;1,4-dimethylbenzene-6-ide;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-m-xylene (553-94-6) → 2,5-dimethylphenylmagnesium bromide (30897-86-0)

Guidance literature:

With magnesium; In tetrahydrofuran; at 0 ℃;

Reference yield: 89.0%

2,5-dimethylphenylmagnesium bromide (30897-86-0) + 3,6-bis(tert-butyldimethylsilyloxy)-9H-xanthen-9-one (121714-18-9) → 9-(2,5-dimethylphenyl)-6-hydroxy-3H-xanthen-3-one

Guidance literature:

2,5-dimethylphenylmagnesium bromide; 3,6-bis(tert-butyldimethylsilyloxy)-9H-xanthen-9-one; In tetrahydrofuran; at 0 ℃; for 0.166667h;

With hydrogenchloride; In tetrahydrofuran;

DOI:10.1021/ja043919h

Reference yield: 89.0%

(η5-C5Me5)Rh{PMe3}Br2 + 2,5-dimethylphenylmagnesium bromide (30897-86-0) → C5(CH3)5RhP(CH3)3(C6H3(CH3)2)Br (90624-56-9)

Guidance literature:

With NH₄Br; In tetrahydrofuran; To a soln. of complex in THF at -40°C the Grignard reagent was added dropwise with a syringe, the mixt. was stirred for 15 min at this temp., allowed to warm to 25°C over 30 min, stirred for 30 min at 25°C, (N2 atm.);; NH4X was added, solvent was removed, ppt. was extd. with CH2Cl2, filtered, concd., chromd. on SiO2 thick-layer plates with CH2Cl2, recrystd. from hexane (-40°C, 1 h), dried in vac.;;

upstream raw materials:

4-bromo-m-xylene

Downstream raw materials:

2-(2,5-dimethylphenyl)ethan-1-ol

2-(2,5-dimethyl-phenyl)-3-methyl-butan-2-ol

acetic acid-[2-(2,5-dimethyl-benzoyl)-anilide]

2-(2,5-Dimethyl-phenyl)-1',2'-epoxy-bicyclohexyl-2-ol

Refernces

• 1、 -. "Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities". Page/Page column 19. . Retrieved 2008/06/13.