Methyl 5-(Dimethylamino)nicotinate

Base Information

• Chemical Name: Methyl 5-(Dimethylamino)nicotinate
• CAS No.: 29898-23-5
• Molecular Formula: C9H12N2O2
• Molecular Weight: 180.21
• Hs Code.: 2933399090
• Mol file: 29898-23-5.mol

Synonyms:Methyl 5-(Dimethylamino)nicotinate;Methyl 5-(Dimethylamino)pyridine-3-carboxylate;

Chemical Property of Methyl 5-(Dimethylamino)nicotinate

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.549
• Boiling Point: 290.852 °C at 760 mmHg
• Flash Point: 129.703 °C
• PSA: 42.43000
• Density: 1.137 g/cm³
• LogP: 0.93420
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

Methyl5-(dimethylamino)nicotinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 5-(Dimethylamino)nicotinate

There total 2 articles about Methyl 5-(Dimethylamino)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 5-amino-nicotinic acid methyl ester (36052-25-2) → 5-(dimethylamino)pyridine-3-carboxylic acid methyl ester (29898-23-5)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In water; acetonitrile; at 20 ℃; for 18.5h;

Reference yield:

→ 5-(dimethylamino)pyridine-3-carboxylic acid methyl ester (29898-23-5)

Guidance literature:

5-Dimethylaminonicotinsaeure, CH3OH, H2SO4;

upstream raw materials:

formaldehyd

5-amino-nicotinic acid methyl ester

Refernces

• 1、 -. "COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF". Page/Page column 63. . Retrieved 2008/06/13.