2-(4-Benzyloxy-phenyl)-ethylamine

Base Information

• Chemical Name: 2-(4-Benzyloxy-phenyl)-ethylamine
• CAS No.: 51179-05-6
• Molecular Formula: C15H17NO
• Molecular Weight: 227.306
• Hs Code.: 2922199090
• Mol file: 51179-05-6.mol

Synonyms:RARECHEM AL BW 1365;4-Benzyloxyphenethylamine;

Chemical Property of 2-(4-Benzyloxy-phenyl)-ethylamine

Chemical Property:

• Vapor Pressure: 1.1E-05mmHg at 25°C
• Refractive Index: 1.584
• Boiling Point: 370.5 °C at 760 mmHg
• Flash Point: 179.6 °C
• PSA: 35.25000
• Density: 1.079 g/cm³
• LogP: 3.46710

Purity/Quality:

98%min ^*data from raw suppliers

2-[4-(Benzyloxy)phenyl]ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Benzyloxy-phenyl)-ethylamine

There total 17 articles about 2-(4-Benzyloxy-phenyl)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-(benzyloxy)-4-(2-nitroethyl)benzene (99696-06-7) → 2-(4-(benzyloxy)phenyl)ethanamine (51179-05-6)

Guidance literature:

With hydrogen; In ethanol; at 100 ℃; Flow reactor;

DOI:10.1002/asia.202000065

Reference yield: 91.0%

→ 2-(4-(benzyloxy)phenyl)ethanamine (51179-05-6)

Guidance literature:

Reference yield: 86.0%

1-(2'-azidoethyl)-4-(benzyloxy)benzene (74447-33-9) → 2-(4-(benzyloxy)phenyl)ethanamine (51179-05-6)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 7h; Inert atmosphere;

DOI:10.1016/j.ejmech.2019.07.053

upstream raw materials:

1-benzyloxy-4-(2-nitroethenyl)benzene

(E)-1-(benzyloxy)-4-(2-nitrovinyl)benzene

p-benzyloxybenzaldehyde

4-benzyloxybenzyl alcohol

Downstream raw materials:

N-[2-(4-Benzyloxy-phenyl)-ethyl]-3-bromo-propionamide

4-Benzyloxy-N-<3.4-dibenzyloxy-benzyl>-phenaethylamin

[2-(4-benzyloxy-phenyl)-ethyl]-(6-nitro-quinazolin-4-yl)-amine

N-[2-(4-benzyloxy-phenyl)-ethyl]-4-methoxy-benzamide

Refernces

• 1、 Roldán-Pe?a, Jesús M.,Romero-Real,Hicke, Javier,Maya, Inés,Franconetti, Antonio,Lagunes,Padrón, José M.,Petralla, Sabrina,Poeta, Eleonora,Naldi, Marina,Bartolini, Manuela,Monti, Barbara,Bolognesi, Maria L.,López, óscar,Fernández-Bola?os, José G.. "Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors". . . Retrieved 2019/08/02.
• 2、 -. "PTERIDINES AND THEIR USE AS AGROCHEMICALS". . . Retrieved 2011/04/14.