Phenol, 4-amino-2-methoxy-6-methyl- (9CI)

Base Information

• Chemical Name: Phenol, 4-amino-2-methoxy-6-methyl- (9CI)
• CAS No.: 408309-38-6
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.181
• Mol file: 408309-38-6.mol

Synonyms:4-Amino-2-methoxy-6-methylphenol;2-Methoxy-4-amino-6-methylphenol;

Chemical Property of Phenol, 4-amino-2-methoxy-6-methyl- (9CI)

Chemical Property:

• Boiling Point: 315.5 °C at 760 mmHg
• Flash Point: 144.6 °C
• PSA: 55.48000
• Density: 1.174 g/cm³
• LogP: 1.87260

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 4-amino-2-methoxy-6-methyl- (9CI)

There total 7 articles about Phenol, 4-amino-2-methoxy-6-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-6-methyl-[1,4]benzoquinone-4-oxime (857009-39-3) → 4-Amino-2-methoxy-6-methyl-phenol (408309-38-6)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

DOI:10.1039/jr9550002619

Reference yield:

2-methoxy-6-methyl-4-nitrophenol (408335-62-6) → 4-Amino-2-methoxy-6-methyl-phenol (408309-38-6)

Guidance literature:

With sodium hydroxide; sodium dithionite;

DOI:10.1039/jr9550002619

Reference yield:

2-methyl-6-methoxyphenol (2896-67-5) → 4-Amino-2-methoxy-6-methyl-phenol (408309-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic sodium ethylate

2: SnCl₂; concentrated aqueous HCl

With hydrogenchloride; sodium ethanolate; tin(ll) chloride;

DOI:10.1039/jr9550002619

upstream raw materials:

2-methoxy-6-methyl-[1,4]benzoquinone-4-oxime

2-methoxy-6-methyl-4-nitrophenol

2-methyl-6-methoxyphenol

2-methoxy-6-methyl-1,4-benzoquinone

Downstream raw materials:

2-methoxy-6-methyl-[1,4]benzoquinone-4-oxime

2-methoxy-6-methyl-1,4-benzoquinone