DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT

Base Information

• Chemical Name: DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT
• CAS No.: 68695-48-7
• Molecular Formula: C24H54NO4P
• Molecular Weight: 451.671
• Hs Code.: 2923900090
• Mol file: 68695-48-7.mol

Synonyms:Tetra-n-butylammonium Di-tert-butylphosphate;

Chemical Property of DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT

Chemical Property:

• PSA: 68.40000
• LogP: 8.15880
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Tetra-n-butylammonium di-tert-butylphosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT

There total 7 articles about DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

phosphoric acid di-tert-butyl ester (33494-81-4) + tetra(n-butyl)ammonium hydroxide (2052-49-5) → di-tert-butyl phosphoric acid tetra-n-butylammonium salt (68695-48-7)

Guidance literature:

In water; acetone; Cooling with ice;

Reference yield: 77.0%

phosphoric acid di-tert-butyl ester (33494-81-4) → di-tert-butyl phosphoric acid tetra-n-butylammonium salt (68695-48-7)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In methanol; at 26 ℃; for 0.7h; pH=6.5 - 7.0;

Reference yield:

di-tert-butyl phosphite (13086-84-5) → di-tert-butyl phosphoric acid tetra-n-butylammonium salt (68695-48-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium permanganate; potassium hydrogencarbonate / water / 1.5 h / 20 °C

2: hydrogenchloride / water; methanol / 0 °C

3: methanol / 0 °C

With hydrogenchloride; potassium permanganate; potassium hydrogencarbonate; In methanol; water;

upstream raw materials:

tetra(n-butyl)ammonium hydrogensulfate

potassium di-tert-butylphosphate

phosphoric acid di-tert-butyl ester

tetra(n-butyl)ammonium hydroxide

Downstream raw materials:

di-tert-butyl chloromethyl phosphate

[2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-4,5-difluorophenyl]methyl di-tert-butyl phosphate

bis(4-methoxyphenyl)sulfide

4-Methoxy-benzenethiolatetetrabutyl-ammonium;

Refernces

• 1、 -. "SUBSTITUTED 4-PHENYL-PYRIDINES FOR TREATMENT OF NK-1 RECEPTOR RELATED DISEASES". Paragraph 0182-0184. . Retrieved 2018/10/31.
• 2、 -. "HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF". Page/Page column 66. . Retrieved 2010/12/29.