MECOPROP

Base Information

• Chemical Name: MECOPROP
• CAS No.: 7085-19-0
• Molecular Formula: C10H11ClO3
• Molecular Weight: 214.65
• Hs Code.: 29189900
• Mol file: 7085-19-0.mol

Synonyms:2-(4-CHLORO-2-METHYLPHENOXY)PROPIONIC ACID;2-(2-METHYL-4-CHLOROPHENOXY)PROPIONIC ACID;AKOS B030311;ACTRIL M;A-(4-CHLORO-2-METHYLPHENOXY)PROPIONIC ACID;MECOPROP;MEPRO(R);MCPP(R)

Chemical Property of MECOPROP

Chemical Property:

• Refractive Index: 1.5390 (estimate)
• Boiling Point: 308.11°C (rough estimate)
• Flash Point: 100 °C
• PSA: 46.53000
• Density: 1.2413 (rough estimate)
• LogP: 2.50030
• Storage Temp.: 2-8°C

Purity/Quality:

99.9% ^*data from raw suppliers

Mecoprop PESTANAL?, analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N,F
• Hazard Codes: Xn,N,F
• Statements: 22-38-41-50/53-52/53-36-20/21/22-11
• Safety Statements: 13-26-37/39-60-61-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of MECOPROP

There total 32 articles about MECOPROP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4-chloro-2-methyl-1-[(3E)-pent-3-en-2-yloxy]benzene → (RS)-2-(4-chloro-o-tolyloxy)propionic acid (93-65-2,18221-59-5,7085-19-0)

Guidance literature:

4-chloro-2-methyl-1-[(3E)-pent-3-en-2-yloxy]benzene; With oxygen; ozone; acetic acid; In dichloromethane; at 0 ℃;

With selenium(IV) oxide; dihydrogen peroxide; In dichloromethane; at 0 - 20 ℃; for 48h; Reagent/catalyst; Inert atmosphere;

DOI:10.1134/S1070428018090075

Reference yield: 45.0%

(R)-2-(4-chloro-2-methylphenoxy)propionic acid ethyl ester (66513-22-2,40390-11-2) → (R)-Mecoprop (16484-77-8,18221-59-5,7085-19-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.1016/S0014-827X(01)01041-2

Reference yield:

Preventol B 2 → (RS)-2-(4-chloro-o-tolyloxy)propionic acid (93-65-2,18221-59-5,7085-19-0)

Guidance literature:

With methanol; potassium hydroxide; In various solvent(s); at 25 ℃; pH=10; Further Variations:; pH-values; Kinetics;

DOI:10.1021/es980318f

upstream raw materials:

(RS)-2-(4-chloro-o-tolyloxy)propionic acid

methyl R-2-(4-chloro-2-methylphenoxy)propanoate

(R)-1-(4-pyridinyl)ethanol

2-(4-Chlor-2-methylphenoxy)propionsaeureanhydrid

Downstream raw materials:

2-(4-Chloro-2-methyl-phenoxy)-N-phenyl-propionamide

(S)-(+)-2-methyl-2-(4-chloro-2-methylphenoxy)ethanol

(2-dimethylamino)ethyl (±)-2-(4-chloro-2-methylphenoxy)propionate

Refernces

• 1、 Hellinghausen, Garrett,Lopez, Diego A.,Lee, Jauh T.,Wang, Yadi,Weatherly, Choyce A.,Portillo, Abiud E.,Berthod, Alain,Armstrong, Daniel W.. "Evaluation of the Edman degradation product of vancomycin bonded to core-shell particles as a new HPLC chiral stationary phase". . p. 1067 - 1078. Retrieved 2018/08/01.
• 2、 Tengeiji, Atsushi,Nakata, Kenya,Ono, Keisuke,Shiina, Isamu. "A new method for production of chiral 2-aryloxypropanoic acids using effective kinetic resolution of racemic 2-aryloxycarboxylic acids". . p. 1227 - 1252. Retrieved 2013/08/23.