CH₂C(Sn(CH₃)2Cl)CH₂CH(OH)CHCHC₆H₅

Base Information

• Chemical Name: CH₂C(Sn(CH₃)2Cl)CH₂CH(OH)CHCHC₆H₅
• CAS No.: 125405-20-1
• Molecular Formula: C₁₄H₁₉ClOSn
• Molecular Weight: 357.467
• Mol file: 125405-20-1.mol

Synonyms:

Chemical Property of CH₂C(Sn(CH₃)2Cl)CH₂CH(OH)CHCHC₆H₅

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of CH₂C(Sn(CH₃)2Cl)CH₂CH(OH)CHCHC₆H₅

There total 2 articles about CH₂C(Sn(CH₃)2Cl)CH₂CH(OH)CHCHC₆H₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2,3-bis(trimethylstannyl)-1-propene (90886-11-6) + 3-phenyl-propenal (104-55-2) → CH2C(Sn(CH3)2Cl)CH2CH(OH)CHCHC6H5 (125405-20-1) + isopropenyltrimethylstannane (3043-46-7)

Guidance literature:

With boron trifluoride diethyl etherate; ammonium chloride; In dichloromethane; Ar; -78°C; slow addn. of BF3*Et2O; after 1 h hydrolysed with NH4Cl/H2O at room temp.;; aq. layer extd. with Et2O; combined organic layers dried over Na2SO4; evapd.; recrystd. from CH2Cl2/ether.; identified by 1H-, 13C- and 119Sn- spectroscopy;;

DOI:10.1016/0022-328X(91)86010-N

Reference yield: 10.0%

2,3-bis(trimethylstannyl)-1-propene (90886-11-6) + 3-phenyl-propenal (104-55-2) → CH2C(Sn(CH3)3)CH2CH(OH)CHCHC6H5 + CH2C(Sn(CH3)2Cl)CH2CH(OH)CHCHC6H5 (125405-20-1) + isopropenyltrimethylstannane (3043-46-7)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; Ar; -78°C; slow addn. of BF3*Et2O; yield RSnMe2OH and RSnMe3: 70% (80/20);; aq. layer extd. with Et2O; combined organic layers dried over Na2SO4; evapd.; identified by 1H-, 13C- and 119Sn- spectroscopy;;

DOI:10.1016/0022-328X(91)86010-N

upstream raw materials:

2,3-bis(trimethylstannyl)-1-propene

3-phenyl-propenal

Refernces