butyl 3-hydroxynaphthalene-2-carboxylate

Base Information

• Chemical Name: butyl 3-hydroxynaphthalene-2-carboxylate
• CAS No.: 7260-07-3
• Molecular Formula: C15H16 O3
• Molecular Weight: 244.29
• Mol file: 7260-07-3.mol

Synonyms:2-Naphthoicacid, 3-hydroxy-, butyl ester (7CI,8CI); Butyl3-hydroxy-2-naphthalenecarboxylate; Butyl 3-hydroxy-2-naphthoate; NSC 69142

Chemical Property of butyl 3-hydroxynaphthalene-2-carboxylate

Chemical Property:

• Vapor Pressure: 5.22E-06mmHg at 25°C
• Boiling Point: 370.4°C at 760 mmHg
• Flash Point: 153.3°C
• Density: 1.166g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of butyl 3-hydroxynaphthalene-2-carboxylate

There total 4 articles about butyl 3-hydroxynaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(1H-benzo[d][1,2,3]triazol-1-yl)(3-hydroxynaphthalen-2-yl)methanone (876891-35-9) + butan-1-ol (71-36-3) → butyl 3-hydroxynaphthalene-2-carboxylate (7260-07-3)

Guidance literature:

at 120 ℃; for 0.166667h; microwave irradiation;

DOI:10.1021/jo052293q

Reference yield: 82.0%

3-Hydroxy-2-naphthoic acid (92-70-6) + butan-1-ol (71-36-3) → butyl 3-hydroxynaphthalene-2-carboxylate (7260-07-3)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 24h; Heating;

DOI:10.1016/S0040-4020(01)88318-6

Reference yield:

3-Hydroxy-2-naphthoic acid (92-70-6) → butyl 3-hydroxynaphthalene-2-carboxylate (7260-07-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / tetrahydrofuran / 2 h / 20 °C

2: 84 percent / 0.17 h / 120 °C / microwave irradiation

With thionyl chloride; In tetrahydrofuran;

DOI:10.1021/jo052293q

upstream raw materials:

3-Hydroxy-2-naphthoic acid

butan-1-ol

(1H-benzo[d][1,2,3]triazol-1-yl)(3-hydroxynaphthalen-2-yl)methanone

Downstream raw materials:

Butyl 2,2'-dihydroxy-1,1'-binaphthalene-3-carboxylate

2,2'-Dihydroxy-[1,1']binaphthalenyl-3,3'-dicarboxylic acid dibutyl ester

1,1'-bi-2-naphthol

Refernces

• 1、 Katritzky, Alan R.,Singh, Sanjay K.,Cai, Chunming,Bobrov, Sergey. "Direct synthesis of esters and amides from unprotected hydroxyaromatic and -aliphatic carboxylic acids". . p. 3364 - 3374. Retrieved 2007/10/03.