Technology Process of cis-(D)-Nα-(Boc)-4-aminocyclohexylglycine
There total 9 articles about cis-(D)-Nα-(Boc)-4-aminocyclohexylglycine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
under 760 Torr;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 5.16 g / Et3N / dioxane; H2O / 36 h / Ambient temperature
2: dicyclohexylamine / ethyl acetate / 24 h / Ambient temperature
3: 640 mg / 3M HCl / ethyl acetate / 0.25 h / Ambient temperature
4: pyridine / 24 h / Ambient temperature
5: 3.4 g / sodium azide / dimethylformamide; H2O / 6 h / 40 °C
6: H2 / 10percent Pd/C / ethanol / Ambient temperature
With
pyridine; hydrogenchloride; sodium azide; hydrogen; triethylamine; N-cyclohexyl-cyclohexanamine;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; water; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 5.16 g / Et3N / dioxane; H2O / 36 h / Ambient temperature
2: dicyclohexylamine / ethyl acetate / 24 h / Ambient temperature
3: pyridine / 24 h / Ambient temperature
4: 3.4 g / sodium azide / dimethylformamide; H2O / 6 h / 40 °C
5: H2 / 10percent Pd/C / ethanol / Ambient temperature
With
pyridine; sodium azide; hydrogen; triethylamine; N-cyclohexyl-cyclohexanamine;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; water; ethyl acetate; N,N-dimethyl-formamide;