C₂₀H₁₈ClNO

Base Information

• Chemical Name: C₂₀H₁₈ClNO
• CAS No.: 1352632-28-0
• Molecular Formula: C₂₀H₁₈ClNO
• Molecular Weight: 323.822
• Mol file: 1352632-28-0.mol

Synonyms:

Chemical Property of C₂₀H₁₈ClNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₁₈ClNO

There total 4 articles about C₂₀H₁₈ClNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-oxoindole (59-48-3) → C20H18ClNO (1352632-28-0)

Guidance literature:

Multi-step reaction with 2 steps

1: trichlorophosphate / chloroform / 5 h / Heating

2: potassium carbonate / acetone / 10 h / Reflux

With potassium carbonate; trichlorophosphate; In chloroform; acetone;

DOI:10.1002/ejoc.201100876

Reference yield:

4-phenylbuta-3-en-1-ol (770-36-5,20047-19-2,937-58-6) → C20H18ClNO (1352632-28-0)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus tribromide / benzene / Cooling with ice; Reflux

2: potassium carbonate / acetone / 10 h / Reflux

With phosphorus tribromide; potassium carbonate; In acetone; benzene;

DOI:10.1002/ejoc.201100876

Reference yield:

benzaldehyde (100-52-7) → C20H18ClNO (1352632-28-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / tetrahydrofuran / 12 h / Reflux

2: phosphorus tribromide / benzene / Cooling with ice; Reflux

3: potassium carbonate / acetone / 10 h / Reflux

With phosphorus tribromide; potassium carbonate; In tetrahydrofuran; acetone; benzene; 1: Wittig reaction;

DOI:10.1002/ejoc.201100876

upstream raw materials:

2-oxoindole

1-(2-chloro-1H-indol-3-yl)ethanone

(4-bromo-1-buten-1-yl)benzene

4-phenylbuta-3-en-1-ol

Refernces