Epietoxadrol hydrochloride

Base Information

• Chemical Name: Epietoxadrol hydrochloride
• CAS No.: 117019-54-2
• Molecular Formula: C₁₆H₂₃NO₂*ClH
• Molecular Weight: 297.825
• Mol file: 117019-54-2.mol

Synonyms:

Chemical Property of Epietoxadrol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Epietoxadrol hydrochloride

There total 3 articles about Epietoxadrol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dexoxadrol (4741-41-7) → Epietoxadrol hydrochloride (117019-54-2,3666-68-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / 1.0 N HCl / methanol; H₂O / 10 h / 40 °C

2: p-toluenesulfonic acid monohydrate / nitromethane / 0.17 h / Heating

With hydrogenchloride; toluene-4-sulfonic acid; In methanol; nitromethane; water;

DOI:10.1021/jm00120a004

Reference yield:

propiophenone dimethyl acetal (25310-92-3) + α-(S,S)-1-(2-piperidyl)-1,2-ethanediol hydrochloride (30162-99-3) → Epietoxadrol hydrochloride (117019-54-2,3666-68-0) + Etoxadrol hydrochloride (23239-37-4,3666-68-0)

Guidance literature:

With toluene-4-sulfonic acid; In nitromethane; for 0.166667h; Heating;

DOI:10.1021/jm00120a004

Reference yield:

→ (+)-2-(2-Ethyl-2-phenyl-1.3-dioxolan-4-yl)-piperidin Hydrochloride (23239-37-4,117019-54-2,3666-68-0)

Guidance literature:

aus (-)-2-Piperidyl-1.2-ethandiol*HCl u. Ethylbenzoyl-dipropylketal;

upstream raw materials:

propiophenone dimethyl acetal

α-(S,S)-1-(2-piperidyl)-1,2-ethanediol hydrochloride

dexoxadrol

Refernces