Technology Process of alterlactone
There total 6 articles about alterlactone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethanol; ethyl acetate;
at 20 ℃;
for 5h;
DOI:10.1055/s-0031-1290135
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; palladium diacetate; caesium carbonate / 1,4-dioxane; water / 20 h / 80 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 5 h / 20 °C
With
2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate;
In
1,4-dioxane; ethanol; water; ethyl acetate;
1: Suzuki coupling;
DOI:10.1055/s-0031-1290135
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diisobutylaluminium hydride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere
2: 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; palladium diacetate; caesium carbonate / 1,4-dioxane; water / 20 h / 80 °C / Inert atmosphere
3: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 5 h / 20 °C
With
2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; palladium 10% on activated carbon; hydrogen; palladium diacetate; diisobutylaluminium hydride; caesium carbonate;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water; ethyl acetate;
2: Suzuki coupling;
DOI:10.1055/s-0031-1290135
