(R)-2-methylamino-1-cyclohexyl-propane

Base Information

• Chemical Name: (R)-2-methylamino-1-cyclohexyl-propane
• CAS No.: 6556-29-2
• Molecular Formula: C₁₀H₂₁N
• Molecular Weight: 155.283
• UNII: 81UZ68T08H
• Nikkaji Number: J215.791H
• Wikidata: Q27269273
• Mol file: 6556-29-2.mol

Synonyms:D-Propylhexedrine;(+)-Propylhexedrine;Propylhexedrine, (+)-;Propylhexedrine D-form [MI];UNII-81UZ68T08H;81UZ68T08H;Cyclohexaneethanamine, N,alpha-dimethyl-, (R)-;6556-29-2;(R)-propylhexedrine;Cyclohexaneethanamine, N,.alpha.-dimethyl-, (R)-;PROPYLHEXEDRINE, (R)-;Q27269273

Chemical Property of (R)-2-methylamino-1-cyclohexyl-propane

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 155.167399674
• Heavy Atom Count: 11
• Complexity: 95

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CC1CCCCC1)NC
• Isomeric SMILES: C[C@H](CC1CCCCC1)NC

Technology Process of (R)-2-methylamino-1-cyclohexyl-propane

There total 3 articles about (R)-2-methylamino-1-cyclohexyl-propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-methylamino-1-phenylpropane (33817-09-3) → (R)-2-methylamino-1-cyclohexyl-propane (6556-29-2,3595-11-7)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

DOI:10.1021/ja01197a039

Reference yield:

propylhexedrine (101-40-6,3595-11-7) → (R)-2-methylamino-1-cyclohexyl-propane (6556-29-2,3595-11-7)

Guidance literature:

With L-Tartaric acid;

Reference yield:

4-cyclohexyl-butan-2-one (103-78-6) → (R)-2-methylamino-1-cyclohexyl-propane (6556-29-2,3595-11-7)

Guidance literature:

Multi-step reaction with 2 steps

1: water / 180 °C / beim Erhitzen des Reaktionsprodukts mit wss. Schwefelsaeure <50prozentig>

2: L_g-tartaric acid

With L-Tartaric acid; water;

upstream raw materials:

(R)-2-methylamino-1-phenylpropane

propylhexedrine

4-cyclohexyl-butan-2-one