C₁₁H₂₁N

Base Information

• Chemical Name: C₁₁H₂₁N
• CAS No.: 1030321-79-9
• Molecular Formula: C₁₁H₂₁N
• Molecular Weight: 167.294
• Mol file: 1030321-79-9.mol

Synonyms:

Chemical Property of C₁₁H₂₁N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₂₁N

There total 5 articles about C₁₁H₂₁N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-6-cyclohexylpiperidin-2-one (1296689-53-6) → C11H21N (1030321-79-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 50 ℃;

DOI:10.1016/j.tetlet.2011.01.090

Reference yield:

(+/-)-2-cyclohexyl-piperidine (56528-77-9) → C11H21N (1030321-79-9)

Guidance literature:

With D-glucose; (R)-6-hydroxy-D-nicotine oxidase from E_. coli; (R)-selective imine reductase; In aq. phosphate buffer; at 30 ℃; for 24h; pH=7.4; enantioselective reaction; Enzymatic reaction;

DOI:10.1002/cctc.201500822

Reference yield:

methyl (S,E)-5-((R)-1-(naphthalen-1-yl)ethylamino)-5-cyclohexylpent-2-enoate (1296689-51-4) → C11H21N (1030321-79-9)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on carbon; hydrogen / ethyl acetate

2: lithium aluminium tetrahydride / tetrahydrofuran / 50 °C

With lithium aluminium tetrahydride; palladium on carbon; hydrogen; In tetrahydrofuran; ethyl acetate;

DOI:10.1016/j.tetlet.2011.01.090

upstream raw materials:

methyl (S,E)-5-((R)-1-(naphthalen-1-yl)ethylamino)-5-cyclohexylpent-2-enoate

(S)-6-cyclohexylpiperidin-2-one

cyclohexanecarbaldehyde

6-cyclohexyl-2,3,4,5-tetrahydro-pyridine

Downstream raw materials:

C₁₉H₂₇NO₂

Refernces

• 1、 Hussain, Shahed,Leipold, Friedemann,Man, Henry,Wells, Elizabeth,France, Scott P.,Mulholland, Keith R.,Grogan, Gideon,Turner, Nicholas J.. "An (R)-imine reductase biocatalyst for the asymmetric reduction of cyclic imines". . p. 579 - 583. Retrieved 2015/03/05.