2-propylmaleic acid

Base Information

• Chemical Name: 2-propylmaleic acid
• CAS No.: 13074-61-8
• Molecular Formula: C₇H₁₀O₄
• Molecular Weight: 158.154
• Mol file: 13074-61-8.mol

Synonyms:

Chemical Property of 2-propylmaleic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-propylmaleic acid

There total 1 articles about 2-propylmaleic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + ethyl 2-oxovalerate (50461-74-0) → 2-propylmaleic acid (13074-61-8) + n-propylfumaric acid (5469-28-3) + 2-propylidenesuccinic acid (5796-70-3)

Guidance literature:

With potassium hydroxide; sodium hydride; Yield given. Multistep reaction. Yields of byproduct given; 1.) diethyl ether, -78 deg C, 3 h then room temperature, 2.) ethanol-water 1 : 1, reflux;

DOI:10.1016/S0040-4020(01)85677-5

Reference yield: 84.4%

2-propylmaleic acid (13074-61-8) → n-propylfumaric acid (5469-28-3)

Guidance literature:

Irradiation;

DOI:10.1016/S0040-4020(01)85677-5

Reference yield:

2-propylmaleic acid (13074-61-8) → propyl-succinic acid (618-57-5)

Guidance literature:

With sodium amalgam;

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

ethyl 2-oxovalerate

Downstream raw materials:

propyl-succinic acid

n-propylfumaric acid

Refernces