Technology Process of 2-azido-2-(3,5-dimethylphenyl)ethanol
There total 3 articles about 2-azido-2-(3,5-dimethylphenyl)ethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium azide; acetic acid;
In
water; acetone;
at 50 ℃;
Inert atmosphere;
DOI:10.1021/ja111700e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C
1.2: 1.33 h / -78 - 20 °C / Inert atmosphere
2.1: water; potassium hydroxide / acetonitrile / 4 h / 60 °C / Inert atmosphere
3.1: sodium azide; acetic acid / water; acetone / 50 °C / Inert atmosphere
With
n-butyllithium; sodium azide; water; acetic acid; potassium hydroxide;
In
tetrahydrofuran; hexane; water; acetone; acetonitrile;
DOI:10.1021/ja111700e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: water; potassium hydroxide / acetonitrile / 4 h / 60 °C / Inert atmosphere
2: sodium azide; acetic acid / water; acetone / 50 °C / Inert atmosphere
With
sodium azide; water; acetic acid; potassium hydroxide;
In
water; acetone; acetonitrile;
DOI:10.1021/ja111700e