2-Pyrimidinecarboxylic acid, 4,6-diphenyl-, 4-cyanophenyl ester

Base Information

• Chemical Name: 2-Pyrimidinecarboxylic acid, 4,6-diphenyl-, 4-cyanophenyl ester
• CAS No.: 106307-62-4
• Molecular Formula: C₂₄H₁₅N₃O₂
• Molecular Weight: 377.402
• Mol file: 106307-62-4.mol

Synonyms:

Chemical Property of 2-Pyrimidinecarboxylic acid, 4,6-diphenyl-, 4-cyanophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Pyrimidinecarboxylic acid, 4,6-diphenyl-, 4-cyanophenyl ester

There total 2 articles about 2-Pyrimidinecarboxylic acid, 4,6-diphenyl-, 4-cyanophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,6-diphenyl-2-pyrimidinecarboxylic acid (6483-96-1) → p-Cyanophenyl 4,6-Diphenylpyrimidine-2-carboxylate (106307-62-4)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / dimethylformamide / benzene / 24 h / Heating

2: pyridine / 120 h / Ambient temperature

With pyridine; thionyl chloride; N,N-dimethyl-formamide; In benzene;

DOI:10.1007/BF00515002

Reference yield:

4-cyanophenol (767-00-0) + 4,6-diphenyl-2-pyrimidinecarboxylic acid chloroanhydride (60007-31-0) → p-Cyanophenyl 4,6-Diphenylpyrimidine-2-carboxylate (106307-62-4)

Guidance literature:

With pyridine; for 120h; Yield given; Ambient temperature;

DOI:10.1007/BF00515002

upstream raw materials:

4-cyanophenol

4,6-diphenyl-2-pyrimidinecarboxylic acid chloroanhydride

4,6-diphenyl-2-pyrimidinecarboxylic acid

Refernces