C₂₀H₂₀FNO₃

Base Information

• Chemical Name: C₂₀H₂₀FNO₃
• CAS No.: 1283110-33-7
• Molecular Formula: C₂₀H₂₀FNO₃
• Molecular Weight: 341.382
• Mol file: 1283110-33-7.mol

Synonyms:

Chemical Property of C₂₀H₂₀FNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₀FNO₃

There total 4 articles about C₂₀H₂₀FNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

3-(4-(dimethylamino)phenyl)-7-hydroxy-2H-chromen-2-one + 1-fluoro-3-iodo-propane (462-40-8) → C20H20FNO3 (1283110-33-7)

Guidance literature:

With cerium (III) carbonate; In acetonitrile; for 3h; Inert atmosphere; Reflux;

DOI:10.1021/jm101489w

Reference yield:

3-(4-(dimethylamino)phenyl)-2-oxo-2H-chromen-7-yl acetate → C20H20FNO3 (1283110-33-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / methanol; water / 4 h / Reflux

2: cerium (III) carbonate / acetonitrile / 3 h / Inert atmosphere; Reflux

With hydrogenchloride; cerium (III) carbonate; In methanol; water; acetonitrile;

DOI:10.1021/jm101489w

Reference yield:

2-[4-(dimethylamino)phenyl]acetic acid (17078-28-3) → C20H20FNO3 (1283110-33-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate / Reflux

2: hydrogenchloride / methanol; water / 4 h / Reflux

3: cerium (III) carbonate / acetonitrile / 3 h / Inert atmosphere; Reflux

With hydrogenchloride; cerium (III) carbonate; sodium acetate; In methanol; water; acetonitrile;

DOI:10.1021/jm101489w

upstream raw materials:

1-fluoro-3-iodo-propane

2-[4-(dimethylamino)phenyl]acetic acid

2,4-Dihydroxybenzaldehyde

Refernces