Cyclohexyldiphenylphosphine oxide

Base Information

• Chemical Name: Cyclohexyldiphenylphosphine oxide
• CAS No.: 13689-20-8
• Molecular Formula: C18H21OP
• Molecular Weight: 284.338
• Hs Code.: 2902909090
• European Community (EC) Number: 237-204-6
• DSSTox Substance ID: DTXSID50160002
• Nikkaji Number: J277.994C
• Wikidata: Q83028381
• Mol file: 13689-20-8.mol

Synonyms:Cyclohexyldiphenylphosphine oxide;13689-20-8;Diphenyl(cyclohexyl)phosphine oxide;Phosphine oxide, cyclohexyldiphenyl-;[cyclohexyl(phenyl)phosphoryl]benzene;C18H21OP;EINECS 237-204-6;[cyclohexyl(phenyl)phosphoroso]benzene;SCHEMBL778610;(Diphenylphosphinyl)cyclohexane;DTXSID50160002;(cyclohexyl-phenylphosphoryl)benzene;C18-H21-O-P;MFCD00014301;AKOS015889096;AS-62577;C3310;CS-0156064;FT-0624204;FT-0624223;F10240;A807157;J-006935

Chemical Property of Cyclohexyldiphenylphosphine oxide

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 3.7E-06mmHg at 25°C
• Melting Point: 168-172 °C(lit.)
• Refractive Index: 1.568
• Boiling Point: 397.2 °C at 760 mmHg
• Flash Point: 194 °C
• PSA: 26.88000
• Density: 1.1 g/cm³
• LogP: 4.33320
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Toluene
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 284.133002287
• Heavy Atom Count: 20
• Complexity: 311

Purity/Quality:

98% ^*data from raw suppliers

Cyclohexyldiphenylphosphine Oxide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Cyclohexyldiphenylphosphine oxide

There total 31 articles about Cyclohexyldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1-hydroxycyclohexyl)diphenylphosphine oxide (20187-71-7) → (cyclohexyl)diphenylphosphane oxide (13689-20-8)

Guidance literature:

With diphosphorus tetraiodide; In carbon disulfide; for 24h; Ambient temperature;

DOI:10.1246/cl.1983.1673

Reference yield: 85.0%

Diphenylphosphine oxide (4559-70-0) + cyclohexene (110-83-8) → (cyclohexyl)diphenylphosphane oxide (13689-20-8)

Guidance literature:

With sodium carbonate; salicylaldehyde; In water; Irradiation;

DOI:10.1039/d1gc00374g

Reference yield: 83.0%

1-bromocyclohexane (108-85-0) + Diphenylphosphine oxide (4559-70-0) → (cyclohexyl)diphenylphosphane oxide (13689-20-8)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; lithium methanolate; In 1-methyl-pyrrolidin-2-one; at 40 ℃; for 24h;

DOI:10.1039/c7ra02766d

upstream raw materials:

diphenyl-phosphinic acid

cyclohexanone

diphenylphosphane

phenyllithium

Downstream raw materials:

cyclohexyl(phenyl)phosphinic acid

diphenylcyclohexylphosphine-borane complex

cyclohexyldiphenylphosphine

Refernces

• 1、 Screttas,C.,Isbell,A.F.. "-". . p. 2573 - 2577. Retrieved 1962.
• 2、 Mashita, Takanori,Tsushima, Satoru,Takao, Koichiro. "Controlling the lability of uranyl(vi) through intramolecular π-π Stacking". . p. 13072 - 13080. Retrieved 2018.
• 3、 Cao, Peng,Chen, Tian,Fan, Jiaye,Hu, Ping,Li, Miaomiao,Li, Qianggen,Li, Yang,Wang, Bi-Qin,Wang, Simin,Xiong, Fuying,Yuan, Zeqin. "Visible light induced hydrophosphinylation of unactivated alkenes catalyzed by salicylaldehyde". supporting information. p. 3600 - 3606. Retrieved 2021/06/06.
• 4、 Huang, Zhenjun,Liu, Wei,Li, Sen,Yang, Yutian,Guo, Shengmei,Cai, Hu. "Potassium carbonate promoted nucleophilic addition of alkenes with phosphites". supporting information. p. 1295 - 1297. Retrieved 2020/08/21.