Cyanic acid, 2-methylphenyl ester

Base Information

• Chemical Name: Cyanic acid, 2-methylphenyl ester
• CAS No.: 1123-89-3
• Molecular Formula: C8H7NO
• Molecular Weight: 133.15
• Mol file: 1123-89-3.mol

Synonyms:

Chemical Property of Cyanic acid, 2-methylphenyl ester

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyanic acid, 2-methylphenyl ester

There total 2 articles about Cyanic acid, 2-methylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

bromocyane (506-68-3) + ortho-cresol (95-48-7,77504-84-8) → 2-Methyl-phenylcyanat (1123-89-3)

Guidance literature:

With triethylamine; In tetrachloromethane; water; Cooling;

DOI:10.15227/orgsyn.061.0035

Reference yield:

→ 2-Methyl-phenylcyanat (1123-89-3)

Guidance literature:

Darst. gemaess Ber. 97, 3012 (1964);

Reference yield: 93.7%

(3,5-dibromophenoxy)-tert-butyldimethylsilane (136386-79-3) + 2-Methyl-phenylcyanat (1123-89-3) → C13H18BrNOSi (1089178-86-8) + 1-bromo-3-[(tert-butyldimethylsilyl)oxy]benzene (65423-56-5)

Guidance literature:

(3,5-dibromophenoxy)-tert-butyldimethylsilane; With isopropylmagnesium chloride; In tetrahydrofuran; at 20 - 65 ℃;

2-Methyl-phenylcyanat; In tetrahydrofuran; n-heptane; at 10 ℃;

upstream raw materials:

bromocyane

ortho-cresol

Downstream raw materials:

ethyl (4-nitrobenzoyl)cyanoacetate

(4-Nitrobenzoyl)-(o-tolyloxyiminocarbonyl)-essigsaeureethylester

2-(o-Tolyloxyimino-carbonyl)-acetessigsaeure-(2,4-dimethylanilid)

2-(o-Tolyloxyiminocarbonyl)-acetessigsaeure-(p-chlor-o-toluidid)

Refernces

• 1、 -. "NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS". Page/Page column 36. . Retrieved 2009/01/20.