Technology Process of 5,10-methylidyne-5,6,7,8-tetrahydrofolic acid
There total 5 articles about 5,10-methylidyne-5,6,7,8-tetrahydrofolic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
water;
at 100 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 20 h / Ambient temperature
2: 0.1 M NaOH / H2O / 2 h / 100 °C
With
sodium hydroxide;
In
water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79 percent / ascorbic acid, sodium hydroxide, sodium dithionite / H2O / 0.08 h / Ambient temperature
2: NADPH, bovine liver dihydrofolate reductase, phosphate buffer / 1.67 h / 30 °C
3: 20 h / Ambient temperature
4: 0.1 M NaOH / H2O / 2 h / 100 °C
With
sodium hydroxide; sodium dithionite; phosphate buffer; bovine liver dihydrofolate reductase; NADPH; ascorbic acid;
In
water;
