C₂₁H₃₃NO

Base Information

• Chemical Name: C₂₁H₃₃NO
• CAS No.: 1276118-67-2
• Molecular Formula: C₂₁H₃₃NO
• Molecular Weight: 315.499
• Mol file: 1276118-67-2.mol

Synonyms:

Chemical Property of C₂₁H₃₃NO

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₃₃NO

There total 6 articles about C₂₁H₃₃NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-butane (109-65-9) + N-[1-(3-hydroxyphenyl)cyclohexyl]piperidine (79787-43-2) → C21H33NO (1276118-67-2)

Guidance literature:

With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 80 - 120 ℃;

DOI:10.1016/j.bmcl.2011.02.009

Reference yield:

C13H22N4 (1276118-77-4) → C21H33NO (1276118-67-2)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / -78 - 20 °C

2: boron tribromide / dichloromethane / 3 h / -78 - 0 °C

3: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 80 - 120 °C

With boron tribromide; potassium carbonate; sodium iodide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.02.009

Reference yield:

3-methoxyphencyclidine (72242-03-6) → C21H33NO (1276118-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 3 h / -78 - 0 °C

2: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 80 - 120 °C

With boron tribromide; potassium carbonate; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.02.009

upstream raw materials:

piperidine

1-bromo-butane

N-[1-(3-hydroxyphenyl)cyclohexyl]piperidine

3-methoxyphencyclidine

Refernces