Bis(chloromethyl)dimethylsilane

Base Information

• Chemical Name: Bis(chloromethyl)dimethylsilane
• CAS No.: 2917-46-6
• Molecular Formula: C4H10Cl2Si
• Molecular Weight: 157.115
• European Community (EC) Number: 220-848-7
• DSSTox Substance ID: DTXSID80183426
• Nikkaji Number: J306.845E
• Wikidata: Q83054214
• Mol file: 2917-46-6.mol

Synonyms:Bis(chloromethyl)dimethylsilane;2917-46-6;bis(chloromethyl)-dimethylsilane;Silane, bis(chloromethyl)dimethyl-;(CH3)2Si(CH2Cl)2;EINECS 220-848-7;MFCD00000879;SCHEMBL202964;bis-chloromethyl-dimethyl-silane;Bis(Chloromethyl)Dimethyl-Silane;TVRFAOJPBXYIRM-UHFFFAOYSA-;DTXSID80183426;Bis(chloromethyl)dimethylsilane, 97%;AKOS006222564;BS-43972;B1813;D88862;EN300-113676;J-017417

Chemical Property of Bis(chloromethyl)dimethylsilane

Chemical Property:

• Vapor Pressure: 3.47mmHg at 25°C
• Refractive Index: n20/D 1.460(lit.)
• Boiling Point: 158 °C at 760 mmHg
• Flash Point: 46.1 °C
• PSA: 0.00000
• Density: 1.026 g/cm³
• LogP: 3.08740
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 155.9928822
• Heavy Atom Count: 7
• Complexity: 47.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(chloromethyl)dimethylsilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-10
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(CCl)CCl

Technology Process of Bis(chloromethyl)dimethylsilane

There total 13 articles about Bis(chloromethyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

chlorobromomethane (74-97-5) + dimethylsilicon dichloride (75-78-5,30107-43-8) → bis(chloromethyl)dimethylsilane (2917-46-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -70 ℃; for 27h; Inert atmosphere;

DOI:10.1021/ic101399k

Reference yield: 63.0%

bis(chloromethyl)(methyl)chlorosilane (18171-56-7) → bis(chloromethyl)dimethylsilane (2917-46-6)

Guidance literature:

With CH₃MgBr; In not given;

DOI:10.1021/ja01184a032

Reference yield: 46.0%

chlorine (7782-50-5) + Chloromethyltrimethylsilane (2344-80-1) → (dichloromethyl)trimethylsilane (5926-38-5) + bis(chloromethyl)dimethylsilane (2917-46-6)

Guidance literature:

In neat (no solvent); Irradiation (UV/VIS); irradiation of (CH3)3Si(CH2Cl) and gaseous Cl2 at temp. of boiling xylene;;

DOI:10.1021/ja01148a542

upstream raw materials:

diethyl ether

bis(chloromethyl)(methyl)chlorosilane

methylmagnesium bromide

Chloromethyltrimethylsilane

Downstream raw materials:

Bis-acetoxymethyl-dimethyl-silan

bis(chloromethyl)dimethylsilane

tetramethylsilane

Chloromethyltrimethylsilane

Refernces

• 1、 -. "PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD". Paragraph 0196. . Retrieved 2016/11/21.
• 2、 Fessenden,Coon. "Silicon-substituted medicinal agents. Silacarbamates related to meprobamate.". . p. 604 - 608. Retrieved 2007/10/05.