C₂₀H₂₂N₄O

Base Information

• Chemical Name: C₂₀H₂₂N₄O
• CAS No.: 1418013-22-5
• Molecular Formula: C₂₀H₂₂N₄O
• Molecular Weight: 334.421
• Mol file: 1418013-22-5.mol

Synonyms:

Chemical Property of C₂₀H₂₂N₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₂N₄O

There total 7 articles about C₂₀H₂₂N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

benzyl-cyclopentyl-(5-phenoxymethyl-4-phenyl-4H[1,2,4]triazol-3-yl)amine (1418012-53-9) → C20H22N4O (1418013-22-5)

Guidance literature:

With formic acid; 5%-palladium/activated carbon; at 75 ℃; for 6h;

DOI:10.1021/jm3013213

Reference yield:

2-phenoxyacetic acid (122-59-8) → C20H22N4O (1418013-22-5)

Guidance literature:

Multi-step reaction with 4 steps

1: toluene-4-sulfonic acid / 3 h / Reflux

2: hydrazine hydrate / ethanol / 3 h / Reflux

3: trifluoroacetic acid / tetrahydrofuran / 48 h / Reflux

4: formic acid; 5%-palladium/activated carbon / 6 h / 75 °C

With formic acid; 5%-palladium/activated carbon; toluene-4-sulfonic acid; hydrazine hydrate; trifluoroacetic acid; In tetrahydrofuran; ethanol;

DOI:10.1021/jm3013213

Reference yield:

N-cyclopentylbenzylamine (15205-23-9) → C20H22N4O (1418013-22-5)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol / 2 h / 20 °C

2: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 5 °C

3: trifluoroacetic acid / tetrahydrofuran / 48 h / Reflux

4: formic acid; 5%-palladium/activated carbon / 6 h / 75 °C

With formic acid; 5%-palladium/activated carbon; potassium tert-butylate; trifluoroacetic acid; In tetrahydrofuran; ethanol;

DOI:10.1021/jm3013213

upstream raw materials:

2-phenoxyacetic acid

1-benzyl-1-cyclopentyl-3-phenylthiourea

1-benzyl-1-cyclopentyl-2-methyl-3-phenylisothiourea

phenoxyacetyl hydrazine

Refernces