15205-23-9

Basic information

• Product Name: N-benzylcyclopentanamine
• Synonyms: N-benzylcyclopentanamine;N-Benzyl-N-cyclopentylamine;N-benzylcyclopentanamine(SALTDATA: HCl);N-benzylcyclopentanamine 1HCl;N-Benzylcyclopentylamine;N-cyclopentylBenzenemethanamine
• CAS NO: 15205-23-9
• Molecular Formula: C₁₂H₁₇N
• Molecular Weight: 175.27
• Mol File: 15205-23-9.mol
• Article Data: 28

Chemical Properties

• Melting Point: 158-159 °C
• Boiling Point: 270.5°C at 760 mmHg
• Flash Point: 118.4°C
• Appearance: /
• Density: 0.98g/cm³
• Vapor Pressure: 0.00681mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: 2-8°C
• PKA: 9.95±0.20(Predicted)
• CAS DataBase Reference: N-benzylcyclopentanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzylcyclopentanamine(15205-23-9)
• EPA Substance Registry System: N-benzylcyclopentanamine(15205-23-9)

Safety Data

• Hazardous Substances Data: 15205-23-9(Hazardous Substances Data)

Usage

General Description

N-benzylcyclopentanamine is a chemical compound with the formula C13H17N. It is a derivative of cyclopentanamine, with a benzyl group attached to the nitrogen atom. N-benzylcyclopentanamine has been studied for its potential use in various organic synthesis and drug development processes. It is a colorless to light yellow liquid with a faint odor, and it is slightly soluble in water but more soluble in organic solvents. N-benzylcyclopentanamine has been identified as a potential precursor for the synthesis of various pharmaceuticals and agrochemicals due to its structural and chemical properties. It is also used in the production of various specialty chemicals and as a building block in organic chemistry.

InChI:InChI=1/C12H17N/c1-2-6-11(7-3-1)10-13-12-8-4-5-9-12/h1-3,6-7,12-13H,4-5,8-10H2

Upstream product

• 100-52-7 benzaldehyde 
• 1003-03-8 Cyclopentamine 
• 100-44-7 benzyl chloride 
• 120-92-3 cyclopentanone 
• 932-90-1 Benzaldoxime 
• 96-41-3 Cyclopentanol 
• 100-46-9 benzylamine 
• 100-51-6 benzyl alcohol 
• 100-47-0 benzonitrile 
• 2562-38-1 nitrocyclopentane 
• 100-39-0 benzyl bromide 
• 52703-17-0 N-cyclopentylisopropylamine 
• 766-08-5 methylphenylsilane 
• 622-30-0 N-benzyl hydroxylalmine 

Downstream Products

• 344412-92-6 N-Benzyl-N-cyclopentyl-hydroxylamine 
• 92687-01-9 1-Benzyl-2-hex-1-ynyl-piperidine 
• 92687-02-0 1-(phenylmethyl)-2-[2-(trimethylsilyl)ethynyl]piperidine 
• 92686-96-9 C₁₅H₂₁NO₃ 
• 777-38-8 1-benzyl-2-methylpiperidine 
• 1375801-31-2 benzylcyclopentyl[1.2.4]triazolo[1,5-b]pyridazin-6-ylamine 
• 1356731-56-0 N-benzyl-N-cyclopentylpyridazine-3,6-diamine 
• 4410-78-0 (cyclopentylmethyl)benzene 
• 71475-31-5 1-benzyl-1-cyclopentyl-3-phenylthiourea 
• 1418013-22-5 C₂₀H₂₂N₄O 
• 1418012-53-9 benzyl-cyclopentyl-(5-phenoxymethyl-4-phenyl-4H[1,2,4]triazol-3-yl)amine 
• 1418012-50-6 1-benzyl-1-cyclopentyl-2-methyl-3-phenylisothiourea 

Relevant articles and documents

Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols

A general cobalt-catalyzedN-alkylation of amines with alcohols by borrowing hydrogen methodology to prepare different kinds of amines is reported. The optimal catalyst for this transformation is prepared by pyrolysis of a specific templated material, which is generatedin situby mixing cobalt salts, nitrogen ligands and colloidal silica, and subsequent removal of silica. Applying this novel Co-nanoparticle-based material, >100 primary, secondary, and tertiary amines includingN-methylamines and selected drug molecules were conveniently prepared starting from inexpensive and easily accessible alcohols and amines or ammonia.

Trimethyl Borate-Catalyzed, Solvent-Free Reductive Amination

Solvent-free reductive amination of aldehydes and ketones with aliphatic and aromatic amines in high-to-excellent yields has been achieved with sub-stoichiometric trimethyl borate as promoter and ammonia borane as reductant.

Design, Synthesis, and Structure-Activity Relationship of Economical Triazole Sulfonamide Aryl Derivatives with High Fungicidal Activity

Plant fungal diseases have caused great decreases in crop quality and yield. As one of the considerable agricultural diseases, cucumber downy mildew (CDM) caused by pseudoperonospora cubensis seriously influences the production of cucumber. Amisulbrom is a commercial agricultural fungicide developed by Nissan Chemical, Ltd., for the control of oomycetes diseases that is highly effective against CDM. However, the synthesis of amisulbrom has a high cost because of the introduction of the bromoindole ring. In addition, the continuous use of amisulbrom might increase the risk of resistance development. Hence, there is an imperative to develop active fungicides with new scaffolds but low cost against CDM. In this study, a series of 1,2,4-triazole-1,3-disulfonamide derivatives were designed, synthesized, and screened. Compound 1j showed a comparable fungicidal activity with amisulbrom, but it was low cost and ecofriendly. It has the potential to be developed as a new fungicide candidate against CDM. Further investigations of structure-activity relationship exhibited the structural requirements of 1,2,4-triazole-1,3-disulfonamide and appropriate modification in N-alkyl benzylamine groups with high fungicidal activity. This research will provide powerful guidance for the design of highly active lead compounds with a novel skeleton and low cost.