(2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid

Base Information

• Chemical Name: (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid
• CAS No.: 544697-03-2
• Molecular Formula: C₁₁H₁₂N₂O₆
• Molecular Weight: 268.226
• Mol file: 544697-03-2.mol

Synonyms:

Chemical Property of (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid

There total 8 articles about (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,4,5-trimethyl-phenyl)-acetic acid (3167-01-9) → (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid (544697-03-2)

Guidance literature:

With chloroform; sulfuric acid; nitric acid;

DOI:10.1021/ja01295a029

Reference yield:

1,2,4-Trimethylbenzene (95-63-6) → (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid (544697-03-2)

Guidance literature:

Multi-step reaction with 7 steps

1: zinc cyanide; AlCl₃; benzene / 40 - 45 °C / Einleiten von HCl und Behandeln des Reaktionsgemisches mit wss. HCl

2: zinc; aqueous acetic acid

3: aq.-ethanolic NaOH

4: concentrated aqueous HCl

5: ethanol

6: aqueous sulfuric acid

7: concentrated sulfuric acid; chloroform; nitric acid

With zinc(II) cyanide; hydrogenchloride; sodium hydroxide; aluminium trichloride; ethanol; chloroform; sulfuric acid; nitric acid; acetic acid; zinc; benzene;

DOI:10.1021/ja01295a029

Reference yield:

acetic acid 2,4,5-trimethyl-benzyl ester (18543-92-5) → (2,4,5-trimethyl-3,6-dinitro-phenyl)-acetic acid (544697-03-2)

Guidance literature:

Multi-step reaction with 5 steps

1: aq.-ethanolic NaOH

2: concentrated aqueous HCl

3: ethanol

4: aqueous sulfuric acid

5: concentrated sulfuric acid; chloroform; nitric acid

With hydrogenchloride; sodium hydroxide; ethanol; chloroform; sulfuric acid; nitric acid;

DOI:10.1021/ja01295a029

upstream raw materials:

(2,4,5-trimethyl-phenyl)-acetic acid

1,2,4-Trimethylbenzene

(2,4,5-trimethyl-phenyl)-acetonitrile

acetic acid 2,4,5-trimethyl-benzyl ester