6-S-(4-Chlorophenyl)-6-thio-inosine

Base Information Edit

Chemical Name:6-S-(4-Chlorophenyl)-6-thio-inosine
CAS No.:132089-81-7
Molecular Formula:C16H15ClN4O4S
Molecular Weight:394.838
Hs Code.:
Mol file:132089-81-7.mol

Synonyms:6-S-(4-Chlorophenyl)-6-thio-inosine;

Suppliers and Price of 6-S-(4-Chlorophenyl)-6-thio-inosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-S-(4-Chlorophenyl)-6-thio-inosine
100mg
$ 495.00

Medical Isotopes, Inc.
6-S-(4-Chlorophenyl)-6-thio-inosine
100 mg
$ 950.00

Total 0 raw suppliers

Chemical Property of 6-S-(4-Chlorophenyl)-6-thio-inosine Edit

Chemical Property:

Melting Point:>85°C (dec.)
Boiling Point:718.7±70.0 °C(Predicted)
PKA:13.08±0.70(Predicted)
PSA：138.82000
Density:1.76±0.1 g/cm3(Predicted)
LogP:1.24240
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:: 6-S-(4-Chlorophenyl)-6-thio-inosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 6-S-(4-Chlorophenyl)-6-thio-inosine is an intermediate in the synthesis of Succinoadenosine (S688825), a biochemical marker of adenylosuccinase deficiency - the genetic defect of purine de novo synthesis.

Technology Process of 6-S-(4-Chlorophenyl)-6-thio-inosine

There total 4 articles about 6-S-(4-Chlorophenyl)-6-thio-inosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 132089-80-6
6-(4-chlorophenylsulfanyl)-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

: 132089-81-7
6-(4-chlorophenylthio)-9-β-D-ribofuranosyl-9H-purine

Guidance literature:: With ammonia; In methanol; Ambient temperature;

Reference yield:

: 5987-73-5
2',3',5'-O-triacetyl-6-chloroinosine

: 132089-81-7
6-(4-chlorophenylthio)-9-β-D-ribofuranosyl-9H-purine

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / triethylamine / methanol / 0.5 h / Ambient temperature

2: 97 percent / ammonia / methanol / Ambient temperature

With ammonia; triethylamine; In methanol;

Reference yield:

: 3181-38-2
2',3',5'-tri-O-acetylinosine

: 132089-81-7
6-(4-chlorophenylthio)-9-β-D-ribofuranosyl-9H-purine

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / phosphoryl trichloride, N,N-dimethylaniline / 0.12 h / 115 °C

2: 87 percent / triethylamine / methanol / 0.5 h / Ambient temperature

3: 97 percent / ammonia / methanol / Ambient temperature

With ammonia; N,N-dimethyl-aniline; triethylamine; trichlorophosphate; In methanol;