Phenol, 4-methoxy-, 4-nitrobenzoate

Base Information

• Chemical Name: Phenol, 4-methoxy-, 4-nitrobenzoate
• CAS No.: 13245-59-5
• Molecular Formula: C14H11NO5
• Molecular Weight: 273.245
• Mol file: 13245-59-5.mol

Synonyms:

Chemical Property of Phenol, 4-methoxy-, 4-nitrobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenol, 4-methoxy-, 4-nitrobenzoate

There total 8 articles about Phenol, 4-methoxy-, 4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-nitro-benzoyl chloride (122-04-3) + 4-methoxy-phenol (150-76-5) → 4-methoxyphenyl 4-nitrobenzoate (13245-59-5)

Guidance literature:

With aluminium trichloride; In carbon disulfide;

DOI:10.1007/BF00905470

Reference yield: 86.0%

4-nitrobenzaldehdye (555-16-8) + 4-methoxy-phenol (150-76-5) → 4-methoxyphenyl 4-nitrobenzoate (13245-59-5)

Guidance literature:

With potassium fluoride; In N,N-dimethyl-formamide; at 20 ℃; for 19h;

DOI:10.1002/jccs.201800344

Reference yield: 46.0%

4-methoxyphenylboronic acid (5720-07-0) + 4-nitro-benzoic acid (62-23-7) → 4-methoxyphenyl 4-nitrobenzoate (13245-59-5)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); silver carbonate; In dimethyl sulfoxide; at 120 ℃; for 2h; Sealed vial;

DOI:10.1039/c0cc04104a

upstream raw materials:

O-(4-Nitrobenzyl)-4-methoxyphenol

4-nitro-benzoyl chloride

4-methoxy-phenol

p-methoxybenzoyl p-nitrobenzoyl peroxide

Downstream raw materials:

3-p-Nitrobenzoyl-4-methoxyphenol

3-p-Nitrobenzoyl-4-methoxyphenyl-p-nitrobenzoat

(2-hydroxy-5-methoxyphenyl)(4-nitrophenyl)methanone

Refernces

• 1、 Dai, Jian-Jun,Liu, Jing-Hui,Luo, Dong-Fen,Liu, Lei. "Pd-catalysed decarboxylative Suzuki reactions and orthogonal Cu-based O-arylation of aromatic carboxylic acids". supporting information; experimental part. p. 677 - 679. Retrieved 2011/03/22.
• 2、 Leffler, John E.,Barbas, John T.,Flowers, G. Craig. "p-Methoxybenzoyl p-Nitrobenzoyl Peroxide Revisited: Catalysis by Silica". . p. 2286 - 2287. Retrieved 2007/10/02.