(-)-?-Bromtricyclen

Base Information

• Chemical Name: (-)-?-Bromtricyclen
• CAS No.: 52645-83-7
• Molecular Formula: C₁₀H₁₅Br
• Molecular Weight: 215.133
• Mol file: 52645-83-7.mol

Synonyms:

Chemical Property of (-)-?-Bromtricyclen

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-?-Bromtricyclen

There total 1 articles about (-)-?-Bromtricyclen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoprene epoxide (1838-94-4) → (-)-?-Bromtricyclen (52645-83-7,95910-71-7) + (E)-5-(2,3-Dimethyl-tricyclo[2.2.1.02,6]hept-3-yl)-2-methyl-pent-2-en-1-ol (115-71-9,14490-17-6,19903-72-1,29484-33-1,73307-63-8,95975-80-7,98718-51-5,98718-52-6)

Guidance literature:

With lithium; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1.) 0 deg C 2.) pentane, 0 deg C, 50 min. and room temp. 3o min.;

DOI:10.1016/S0040-4039(01)90159-5

Reference yield: 64.0%

8-bromotricyclene (52645-83-7,95910-71-7) + 3-Methyl-1-butene (563-45-1) → (-)-1,7-dimethyl-7-(4-methyl-3-pentenyl)tricyclo[2.2.1.0(2,6)]heptane (512-61-8,22527-23-7,27353-28-2)

Guidance literature:

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; at -75 ℃; for 0.5h;

DOI:10.1016/S0040-4039(00)73929-3

Reference yield:

(-)-?-Bromtricyclen (52645-83-7,95910-71-7) + isoprene epoxide (1838-94-4) → α-Santalol (115-71-9,14490-17-6,19903-72-1,29484-33-1,73307-63-8,95975-80-7,98718-51-5,98718-52-6) + (E)-5-(2,3-Dimethyl-tricyclo[2.2.1.02,6]hept-3-yl)-2-methyl-pent-2-en-1-ol (115-71-9,14490-17-6,19903-72-1,29484-33-1,73307-63-8,95975-80-7,98718-51-5,98718-52-6)

Guidance literature:

With lithium; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1.) 0 deg C 2.) pentane, 0 deg C, 50 min. and room temp. 30 min.;

DOI:10.1016/S0040-4039(01)90159-5

upstream raw materials:

isoprene epoxide

Downstream raw materials:

α-Santalol

(E)-5-(2,3-Dimethyl-tricyclo[2.2.1.0^2,6]hept-3-yl)-2-methyl-pent-2-en-1-ol

(-)-1,7-dimethyl-7-(4-methyl-3-pentenyl)tricyclo[2.2.1.0(2,6)]heptane

(E)-5-(2,3-dimethyltricyclo<2.2.1.0^2,6>hept-3-yl)-2-methylpent-2-enal

Refernces