2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine

Base Information

• Chemical Name: 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine
• CAS No.: 1426585-25-2
• Molecular Formula: C₄₃H₄₉N₃O₄P₂
• Molecular Weight: 733.827
• Mol file: 1426585-25-2.mol

Synonyms:

Chemical Property of 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine

There total 1 articles about 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-bis-(bromomethyl)pyridine (7703-74-4) + oxide of diphenylphosphite (80413-42-9) → 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine (1426585-25-2) + 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine N-oxide

Guidance literature:

oxide of diphenylphosphite; With n-butyllithium; In hexane; toluene; at 75 - 80 ℃; for 2h; Inert atmosphere;

2,6-bis-(bromomethyl)pyridine; In toluene; at -40 - 80 ℃; for 15h; Overall yield = 61 %; Overall yield = 11.2 g; Inert atmosphere;

DOI:10.1021/ic3025342

Reference yield:

2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine (1426585-25-2) → 2,6-bis[(diphenyl-N,N-diethylcarbamoylmethylphosphine oxide)methyl]pyridine N-oxide

Guidance literature:

With dihydrogen peroxide; acetic acid; In water; at 23 ℃; for 96h; Inert atmosphere;

DOI:10.1021/ic3025342

upstream raw materials:

2,6-bis-(bromomethyl)pyridine

oxide of diphenylphosphite

Refernces