triphenyl (non-3-yn-1-yl)phosphonium bromide

Base Information

• Chemical Name: triphenyl (non-3-yn-1-yl)phosphonium bromide
• CAS No.: 31545-66-1
• Molecular Formula: Br*C₂₇H₃₀P
• Molecular Weight: 465.413
• Mol file: 31545-66-1.mol

Synonyms:

Chemical Property of triphenyl (non-3-yn-1-yl)phosphonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triphenyl (non-3-yn-1-yl)phosphonium bromide

There total 1 articles about triphenyl (non-3-yn-1-yl)phosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-nonyn-1-ol (31333-13-8) → triphenyl (non-3-yn-1-yl)phosphonium bromide (31545-66-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Ph₃P, NBS / CH₂Cl₂

2: toluene / Heating

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; toluene;

DOI:10.1021/jo00018a001

Reference yield:

triphenyl (non-3-yn-1-yl)phosphonium bromide (31545-66-1) → (R)-(+)-γ-nonalactone (63357-96-0,57084-16-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 1) Me₃COK

2: LiOH

3: D₂ / Lindlar

4: O₂ / H₂O / 0 °C / biosynthesis by soybean lipoxygenase (pH 9)

5: HSCH₂CO₂Na

6: H₂O / 48 h / 27 - 30 °C / biosynthesis by Cladosporium suaveolens (CBS 157.58)

With lithium hydroxide; potassium tert-butylate; oxygen; sodium 2-mercaptoacetate; deuterium; Lindlar's catalyst; In water;

DOI:10.1021/jo00018a001

Reference yield:

triphenyl (non-3-yn-1-yl)phosphonium bromide (31545-66-1) → (S)-γ-nonanolide (63357-97-1,57084-16-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 1) Me₃COK

2: LiOH

3: D₂ / Lindlar

4: O₂ / H₂O / 0 °C / biosynthesis by soybean lipoxygenase (pH 9)

5: HSCH₂CO₂Na

6: H₂O / 48 h / 27 - 30 °C / biosynthesis by Cladosporium suaveolens (CBS 157.58)

With lithium hydroxide; potassium tert-butylate; oxygen; sodium 2-mercaptoacetate; deuterium; Lindlar's catalyst; In water;

DOI:10.1021/jo00018a001

upstream raw materials:

3-nonyn-1-ol

Downstream raw materials:

(R)-(+)-γ-nonalactone

(S)-γ-nonanolide

Refernces

• 1、 Rokach, Joshua,Girard, Yves,Guindon, Yvan,Atkinson, Joseph G.,Larue, Marie,et al.. "THE SYNTHESIS OF A LEUKOTRIENE WITH SRS-LIKE ACTIVITY". . p. 1485 - 1488. Retrieved 2007/10/02.