Technology Process of C18H21NO5
There total 7 articles about C18H21NO5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester;
With
N,N,N',N'-tetramethylguanidine;
In
tetrahydrofuran;
at -20 ℃;
for 1h;
3-oxabicyclo[3.2.1]octan-8-one;
In
tetrahydrofuran;
at 20 ℃;
for 72h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: silver(l) oxide / potassium iodide / dichloromethane / 72 h / 20 °C
2.1: potassium carbonate / methanol / 20 °C
3.1: hydrogenchloride; water / 20 °C
4.1: N,N,N',N'-tetramethylguanidine / tetrahydrofuran / 1 h / -20 °C
4.2: 72 h / 20 °C
With
hydrogenchloride; water; potassium carbonate; silver(l) oxide; N,N,N',N'-tetramethylguanidine;
potassium iodide;
In
tetrahydrofuran; methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C
1.2: 0.5 h / -78 - 20 °C
2.1: toluene-4-sulfonic acid / benzene / 4 h / Reflux
3.1: ozone / dichloromethane; methanol / -78 °C
3.2: -78 - 0 °C
4.1: silver(l) oxide / potassium iodide / dichloromethane / 72 h / 20 °C
5.1: potassium carbonate / methanol / 20 °C
6.1: hydrogenchloride; water / 20 °C
7.1: N,N,N',N'-tetramethylguanidine / tetrahydrofuran / 1 h / -20 °C
7.2: 72 h / 20 °C
With
hydrogenchloride; oxalyl dichloride; water; potassium carbonate; toluene-4-sulfonic acid; ozone; dimethyl sulfoxide; silver(l) oxide; N,N,N',N'-tetramethylguanidine;
potassium iodide;
In
tetrahydrofuran; methanol; dichloromethane; benzene;
![3-oxabicyclo[3.2.1]octan-8-one](/Databaselist/images/loading.webp)
