N,N-dimethyl-α-tert-butylbenzylamine

Base Information

• Chemical Name: N,N-dimethyl-α-tert-butylbenzylamine
• CAS No.: 27561-35-9
• Molecular Formula: C₁₃H₂₁N
• Molecular Weight: 191.316
• Mol file: 27561-35-9.mol

Synonyms:

Chemical Property of N,N-dimethyl-α-tert-butylbenzylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dimethyl-α-tert-butylbenzylamine

There total 2 articles about N,N-dimethyl-α-tert-butylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,2-dimethyl-1-phenyl-propylamine (61501-04-0) → N,N-dimethyl-α-tert-butylbenzylamine (27561-35-9)

Guidance literature:

Multistep reaction; (i) aq. HCO₂H, (ii) aq. HCl;

DOI:10.1016/S0040-4020(01)96946-7

Reference yield:

→ N,N-dimethyl-α-tert-butylbenzylamine (27561-35-9)

Guidance literature:

N,N,N-Trimethyl-α-phenyl-neopentylammoniumchlorid, Base, 90grad;

DOI:10.1016/S0040-4039(01)89851-8

Reference yield:

(S(c))-di-μ-chlorobis[2-(1-aminoethyl)phenyl-C,N]dipalladium(II) + N,N-dimethyl-α-tert-butylbenzylamine (27561-35-9) → Pd(C6H4CHCH3NH2)Cl(C(CH3)3CHC6H5N(CH3)2)

Guidance literature:

With KPF₆; In acetonitrile; byproducts: KCl; mixt. Pd complex and amine in MeCN was treated KPF6, KCl was removed, mixt. was stirred at 20°C for 120 h and at 50°C for 48 h; mixt. was chromed.. (eluent - benzene-acetone, 10:1);

DOI:10.1007/s11172-006-0573-8

upstream raw materials:

formaldehyd

2,2-dimethyl-1-phenyl-propylamine