Phosphinous acid, diphenyl-, trimethylsilyl ester

Base Information

• Chemical Name: Phosphinous acid, diphenyl-, trimethylsilyl ester
• CAS No.: 13683-01-7
• Molecular Formula: C15H19OPSi
• Molecular Weight: 274.375
• DSSTox Substance ID: DTXSID70403721
• Nikkaji Number: J922.724E
• Wikidata: Q82207472
• Mol file: 13683-01-7.mol

Synonyms:trimethylsilyl diphenylphosphinite;Phosphinous acid, diphenyl-, trimethylsilyl ester;13683-01-7;DTXSID70403721;BB 0221092

Chemical Property of Phosphinous acid, diphenyl-, trimethylsilyl ester

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 274.09427876
• Heavy Atom Count: 18
• Complexity: 221

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)OP(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Phosphinous acid, diphenyl-, trimethylsilyl ester

There total 13 articles about Phosphinous acid, diphenyl-, trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

chloro-trimethyl-silane (75-77-4) + Diphenylphosphine oxide (4559-70-0) → Diphenylphosphonigsaeure-trimethylsilylester (13683-01-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 25 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01384

Reference yield: 86.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + Diphenylphosphine oxide (4559-70-0) → Diphenylphosphonigsaeure-trimethylsilylester (13683-01-7)

Guidance literature:

at 115 - 120 ℃; for 0.5h;

Reference yield: 85.0%

diphenylphosphine oxide (24630-80-6) + N,N-diethyl-1,1,1-trimethylsilanamine (996-50-9) → Diphenylphosphonigsaeure-trimethylsilylester (13683-01-7)

Guidance literature:

at 160 ℃; for 8h;

upstream raw materials:

chloro-trimethyl-silane

Diphenylphosphine oxide

diphenylphosphine oxide

N,N-diethyl-1,1,1-trimethylsilanamine

Downstream raw materials:

Diphenyltrimethylsiloxy-N-trimethylsilylphosphinimid

<(4-acetamidophenyl)allylaminomethyl>diphenylphosphine oxide

<(1-Trimethylsiloxy-2-methyl-2-phenyl)ethenyl>diphenylphosphinoxid

trimethylsilyl bromide

Refernces

• 1、 Baulin, D. V.,Baulin, V. E.,Karandashev, V. K.,Turanov, A. N.. "Extraction of Uranium(VI), Thorium(IV), and Trivalent Rare Earths from Nitric Acid Solutions with {[2-(2-Diphenylphosphoryl)-4-ethylphenoxy]ethyl}diphenylphosphine Oxide". . p. 1012 - 1019. Retrieved 2020.
• 2、 Bondarenko,Tcarkova,Belus’,Artyushin,Peregudov. "Novel Bis[N-alkyl-N-(2-diphenylphosphinylethyl)]diglycolamides: Synthesis and NMR Spectroscopy Studies". . p. 181 - 189. Retrieved 2021/03/20.
• 3、 Zhang, Jian-Qiu,Han, Li-Biao. "Chlorosilane-Catalyzed Coupling of Hydrogen Phosphine Oxides with Acyl Chlorides Generating Acylphosphine Oxides". supporting information. p. 4633 - 4637. Retrieved 2020/06/23.